Design and synthesis of sulfonamide derivatives of pyrrolidine and piperidine as anti-diabetic agents

Type 2 diabetes (T2D) is a lifestyle disease affecting millions of people worldwide. Various therapies are available for the management of T2D and dipeptidyl peptidase-IV (DPP-IV) inhibition has emerged as a promising therapy for the treatment of type 2 diabetes (T2D). Here we report design, synthes...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of medicinal chemistry 2015-01, Vol.90, p.342-350
Hauptverfasser:	Sharma, Radhika, Soman, Shubhangi S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-diabetic agents Diabetes Mellitus, Type 2 - drug therapy Dose-Response Relationship, Drug Drug Design Humans Hypoglycemic Agents - chemical synthesis Hypoglycemic Agents - chemistry Hypoglycemic Agents - therapeutic use Molecular Docking Simulation Molecular Structure Piperidines - chemistry Piperidines - therapeutic use Pyrrolidines - chemistry Pyrrolidines - therapeutic use Structure-Activity Relationship Sulfonamide derivatives of pyrrolidine and piperidine Sulfonamides - chemical synthesis Sulfonamides - chemistry Sulfonamides - therapeutic use Type 2 diabetes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!