Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4

THE acidic transcriptional activation motif functions in all eukary-otes 1–4 , which suggests that it makes contact with some universal component of the transcriptional apparatus. Transcriptional activation by the yeast regulatory protein GAL4 requires an acidic region at its carboxyl terminus. Here...

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Veröffentlicht in:Nature (London) 1992-06, Vol.357 (6380), p.698-700
Hauptverfasser: Swaffield, Jonathan C, Bromberg, Jacqueline F, Johnston, Stephen A
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Sprache:eng
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