Spontaneous programmed cell death (PCD) process of lymphocytes of FIV-infected cats: Cellular targets and modulation

Unstimulated lymphocytes from FIV-infected cats undergo spontaneous apoptosis in vitro as indicated by internucleosomal DNA fragmentation and hypodiploid DNA content of nuclei. Unlike what is reported in HIV-infected individuals, we observed that cell death of cat lymphocytes was inhibited by activa...

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Veröffentlicht in:	Veterinary immunology and immunopathology 1997-09, Vol.58 (2), p.93-106
Hauptverfasser:	Guiot, Anne-Laure, Rigal, Dominique, Chappuis, Gilles
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - drug effects Bacterial Proteins Cat Cat Diseases - immunology Cat Diseases - pathology Cats Concanavalin A - pharmacology Exotoxins - pharmacology Feline immunodeficiency virus FIV Flow Cytometry Immunodeficiency Virus, Feline In Vitro Techniques Ionomycin - pharmacology Ionophores - pharmacology Kinetics Lentivirus Infections - immunology Lentivirus Infections - pathology Lentivirus Infections - veterinary Lymphocyte Activation Lymphocyte Subsets - drug effects Lymphocyte Subsets - immunology Lymphocyte Subsets - pathology Lymphocytes Lymphocytes - drug effects Lymphocytes - immunology Lymphocytes - pathology Membrane Proteins Phenotype Pokeweed Mitogens - pharmacology Propidium iodide Superantigens - pharmacology Tetradecanoylphorbol Acetate - pharmacology
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