Expression of the protein product of the prostaglandin synthase-2/TIS10 gene in mitogen-stimulated Swiss 3T3 cells

TIS10/PGS-2 encodes a prostaglandin synthase (PGS) distinct from the previously described enzyme PGS-1 (EC 1.14.99.1). We have now generated antipeptide antisera, directed to an amino acid sequence unique to the murine TIS10/PGS-2 protein, which specifically recognize the TIS10/PGS-2 antigen. TIS10/...

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Veröffentlicht in:	The Journal of biological chemistry 1993-03, Vol.268 (8), p.5425-5430
Hauptverfasser:	KUJUBU, D. A, REDDY, S. T, FLETCHER, B. S, HERSCHMAN, H. R
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Cell Line, Transformed Chlorocebus aethiops Cyclooxygenase Inhibitors - pharmacology Dexamethasone - pharmacology Enzyme Induction Enzymes and enzyme inhibitors expression Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology localization Mice Mitogens Molecular Sequence Data Oxidoreductases prostaglandin synthase 2 Prostaglandin-Endoperoxide Synthases - biosynthesis Prostaglandin-Endoperoxide Synthases - genetics Prostaglandin-Endoperoxide Synthases - immunology Swiss 3T3 cells synthesis Tetradecanoylphorbol Acetate - pharmacology
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