Lipidomic analysis of molecular cardiolipin species in livers exposed to ischemia/reperfusion

Transient hepatic ischemia can cause significant liver injury. A central and early event in ischemia/reperfusion (I/R) injury is the impairment of mitochondria. The phospholipid cardiolipin (CL) is required for efficient mitochondrial function. The aim of this study was to analyze composition, conte...

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Veröffentlicht in:	Molecular and cellular biochemistry 2015-02, Vol.400 (1-2), p.253-263
Hauptverfasser:	Martens, Jan-Christian, Keilhoff, Gerburg, Halangk, Walter, Wartmann, Thomas, Gardemann, Andreas, Päge, Ilona, Schild, Lorenz
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biochemistry Biomedical and Life Sciences Cardiolipin Cardiolipins - metabolism Cardiology Citrate (si)-Synthase - metabolism Histology Ischemia Ischemia - metabolism Ischemia - pathology Life Sciences Lipids Lipogenesis Liver Liver - metabolism Liver - pathology Medical Biochemistry Membrane lipids Mitochondria - metabolism Mitochondria - pathology Mitochondrial DNA Oncology Oxidative stress Pharmacology Phospholipids - metabolism Rats Reperfusion Injury - metabolism Reperfusion Injury - pathology
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