Predicting Drug Substances Autoxidation

Purpose Chemical degradation and stability in formulation is a recurrent issue in pharmaceutical development of drugs. The objective of the present study was to develop an in silico risk assessment of active pharmaceutical ingredients (APIs) stability with respect to autoxidation. Methods The chemic...

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Veröffentlicht in:	Pharmaceutical research 2015, Vol.32 (1), p.300-310
Hauptverfasser:	Lienard, P., Gavartin, J., Boccardi, G., Meunier, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Chemical compounds Computer Simulation Drug Stability Hydrogen - chemistry Medical Law Models, Chemical Oxidation Oxidation-Reduction Pharmaceutical Preparations - chemistry Pharmaceutical Preparations - standards Pharmaceutical sciences Pharmacology/Toxicology Pharmacy Research Paper Risk Assessment Thermodynamics
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