Sensitization of ethanol‐induced place preference as a result of up‐regulation of type 1 inositol 1,4,5‐trisphosphate receptors in mouse nucleus accumbens

This study involved mice that received 4 days of ethanol (EtOH) vapor inhalation and then were assessed for type 1 inositol 1,4,5‐trisphosphate receptor (IP3Rs‐1) expression and the development of EtOH‐induced place preference at various time points in withdrawal. IP3R‐1 protein was found to be sign...

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Veröffentlicht in:	Journal of neurochemistry 2014-12, Vol.131 (6), p.836-847
Hauptverfasser:	Kurokawa, Kazuhiro, Mizuno, Koji, Ohkuma, Seitaro
Format:	Artikel
Sprache:	eng
Schlagworte:	2‐APB Animals Behavior, Animal - drug effects Calcium - metabolism conditioned place preference Conditioning (Psychology) - physiology Dopamine - metabolism Ethanol Ethanol - pharmacology FK506 Inositol 1,4,5-Trisphosphate Receptors - metabolism Male Mice Motor Activity - drug effects Neurochemistry nucleus accumbens Nucleus Accumbens - drug effects Nucleus Accumbens - metabolism Rodents Signal transduction Signal Transduction - drug effects Transcription factors Transcriptional Activation - drug effects type 1 inositol 1,4,5‐trisphosphate receptors Up-Regulation - drug effects
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