Detection of HHV-6-specific mRNA and antigens in PBMCs of individuals with chromosomally integrated HHV-6 (ciHHV-6)

After inheritance of chromosomally integrated HHV-6 (ciHHV-6), viral DNA is found in every nucleated cell. The prevalence of ciHHV-6 is estimated to be 0.2-5% of humans. There are conflicting data on the potential for replication, possibly leading to clinical implications. We analysed peripheral blo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical microbiology and infection 2014-10, Vol.20 (10), p.1027-1032
Hauptverfasser:	Strenger, V., Caselli, E., Lautenschlager, I., Schwinger, W., Aberle, S.W., Loginov, R., Gentili, V., Nacheva, E., DiLuca, D., Urban, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antigens, Viral - genetics Antigens, Viral - metabolism Child Chromosomal integration Chromosomes, Human - virology Female Gene expression herpesvirus Herpesvirus 6, Human - genetics Herpesvirus 6, Human - immunology HHV-6 Human herpesvirus 6 Humans Infections Leukocytes, Mononuclear - virology lytic infection Male Medical research Middle Aged Molecular Diagnostic Techniques - methods mRNA Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA, Viral - genetics Roseolovirus Infections - blood Roseolovirus Infections - diagnosis Roseolovirus Infections - virology Sensitivity and Specificity viral antigen viral replication Virus Integration Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!