DNA methylation and mRNA expression profiles in bovine oocytes derived from prepubertal and adult donors

The developmental capacity of oocytes from prepubertal cattle is reduced compared with their adult counterparts, and epigenetic mechanisms are thought to be involved herein. Here, we analyzed DNA methylation in three developmentally important, nonimprinted genes (SLC2A1, PRDX1, ZAR1) and two satelli...

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Veröffentlicht in:	Reproduction (Cambridge, England) England), 2012-09, Vol.144 (3), p.319-330
Hauptverfasser:	Diederich, Mike, Hansmann, Tamara, Heinzmann, Julia, Barg-Kues, Brigitte, Herrmann, Doris, Aldag, Patrick, Baulain, Ulrich, Reinhard, Richard, Kues, Wilfried, Weißgerber, Christian, Haaf, Thomas, Niemann, Heiner
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Bos taurus Cattle DNA Methylation - genetics DNA, Satellite - chemistry Egg Proteins - genetics Epigenesis, Genetic Female Follicle Stimulating Hormone - administration & dosage Glucose Transporter Type 1 - genetics Insulin-Like Growth Factor I - administration & dosage Male Oocytes - chemistry Oocytes - growth & development Oocytes - metabolism Peroxiredoxins - genetics RNA, Messenger - analysis Sexual Maturation Transcriptome
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