Pharmacokinetics of super(18)F-labeled fleroxacin in rabbits with Escherichia coli infections, studied with positron emission tomography

super(18)F-labeled fleroxacin was used to measure the pharmacokinetics of fleroxacin in healthy and infected animals by positron emission tomography (PET) and tissue radioactivity measurements. A pharmacological dose of unlabeled drug (10 mg/kg) was coinjected with the tracer. The pharmacokinetics (...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 1992-01, Vol.36 (10), p.2286-2292
Hauptverfasser:	Fischman, A J, Livni, E, Babich, J, Alpert, N M, Liu, Y-Y, Thom, E, Cleeland, R, Prosser, B L, Callahan, R J
Format:	Artikel
Sprache:	eng
Schlagworte:	Escherichia coli
Online-Zugang:	Volltext
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