Polymeric photosensitizer-embedded self-expanding metal stent for repeatable endoscopic photodynamic therapy of cholangiocarcinoma

Abstract Photodynamic therapy (PDT) is a new therapeutic approach for the palliative treatment of malignant bile duct obstruction. In this study, we designed photosensitizer-embedded self-expanding nonvascular metal stent (PDT-stent) which allows repeatable photodynamic treatment of cholangiocarcino...

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Veröffentlicht in:	Biomaterials 2014-10, Vol.35 (30), p.8487-8495
Hauptverfasser:	Bae, Byoung-chan, Yang, Su-Geun, Jeong, Seok, Lee, Don Haeng, Na, Kun, Kim, Joon Mee, Costamagna, Guido, Kozarek, Richard A, Isayama, Hiroyuki, Deviere, Jacques, Seo, Dong Wan, Reddy, D. Nageshwar
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Bile duct stent Bile Ducts - drug effects Biomedical materials Chlorophyll - analogs & derivatives Chlorophyll - chemistry Chlorophyll - pharmacology Chlorophyll - therapeutic use Cholangiocarcinoma Cholangiocarcinoma - drug therapy Dentistry Ducts Endoscopes Endoscopy Fluorescence HeLa Cells Humans Implantation Membrane-covered self-expanding metal stent (SEMS) Metals - chemistry Mice NIH 3T3 Cells Pheophorbide A Photochemotherapy Photodynamic therapy Photosensitizing Agents - pharmacology Photosensitizing Agents - therapeutic use Polymers - chemical synthesis Polymers - chemistry Stents Subcutaneous Tissue - pathology Surgical implants Swine Swine, Miniature Time Factors Tumors Xenograft Model Antitumor Assays
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