Capillary electrophoretic methods for the screening and determination of pharmacologic adulterants in herbal-based pharmaceutical formulations

This review aims to describe the CE methods utilized for the determination of adulterants in herbal‐based formulations marketed for different therapeutic purposes. The CE methods for screening and determination of pharmacologic adulterants are reviewed on the basis of the CE techniques and their det...

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Veröffentlicht in:	Electrophoresis 2014-11, Vol.35 (21-22), p.3212-3230
Hauptverfasser:	Moreira, Ana Paula L., Martini, Mariele, de Carvalho, Leandro M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adulterants Adulteration Capillarity Capillary electrophoresis Cases (containers) Detectors Drug Contamination Electrophoresis, Capillary - methods Formulations Herbal-based formulations Herbs Joining Mass Spectrometry Pharmaceuticals Plant Preparations - analysis Plant Preparations - chemistry Plant Preparations - standards Screening
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container_end_page	3230
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container_title	Electrophoresis
container_volume	35
creator	Moreira, Ana Paula L. Martini, Mariele de Carvalho, Leandro M.
description	This review aims to describe the CE methods utilized for the determination of adulterants in herbal‐based formulations marketed for different therapeutic purposes. The CE methods for screening and determination of pharmacologic adulterants are reviewed on the basis of the CE techniques and their detection methods. CZE and MEKC methods coupled to optical (UV), capacitively coupled contactless conductivity, and MS detection modes are discussed and reviewed. Worldwide adulteration cases related to pharmaceutical formulations containing herbs as the main active products are presented covering all the works published in the last four decades.
doi_str_mv	10.1002/elps.201400059
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subjects	Adulterants Adulteration Capillarity Capillary electrophoresis Cases (containers) Detectors Drug Contamination Electrophoresis, Capillary - methods Formulations Herbal-based formulations Herbs Joining Mass Spectrometry Pharmaceuticals Plant Preparations - analysis Plant Preparations - chemistry Plant Preparations - standards Screening
title	Capillary electrophoretic methods for the screening and determination of pharmacologic adulterants in herbal-based pharmaceutical formulations
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