Pretreatment with mechano-growth factor E peptide protects bone marrow mesenchymal cells against damage by fluid shear stress

Improper fluid shear stress (FSS) can cause serious damages to bone marrow mesenchymal stem cells (MSCs). Mechano-growth factor (MGF) E peptide pretreatment was proposed to protect MSCs against FSS damage in this study. MSCs were exposed to FSS for 30 min after they were pretreated with MGF E peptid...

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Veröffentlicht in:	Biotechnology letters 2014-12, Vol.36 (12), p.2559-2569
Hauptverfasser:	Lv, Yonggang, Hao, Xiaoying, Sha, Yongqiang, Yang, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Applied Microbiology Biochemistry Biomechanical Phenomena Biomedical and Life Sciences Biophysics Biotechnology Bone marrow Bone Marrow - physiology cell proliferation Cell Proliferation - drug effects Cell Survival - drug effects Damage Fluid dynamics Fluid flow Fluid mechanics Fluids Insulin-Like Growth Factor I - metabolism Life Sciences Mesenchymal Stromal Cells - physiology Microbiology Original Research Paper Peptides Pretreatment Shear stress Stem cells synergism Synergistic effect Tissue engineering viability
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