A biosynthetic pathway for hexanoic acid production in Kluyveromyces marxianus

•Hexanoic acid has been used in diverse industrial applications.•A biosynthetic pathway for hexanoic acid has never been constructed in yeast.•The pathways involving 5–7 genes were constructed in K. marxianus.•AtoB-mediated chain elongation was fast, but was followed by sudden decrease.•MCT1-mediate...

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Veröffentlicht in:	Journal of biotechnology 2014-07, Vol.182-183, p.30-36
Hauptverfasser:	Cheon, Yuna, Kim, Jun-Seob, Park, Jun-Bum, Heo, Paul, Lim, Jae Hyung, Jung, Gyoo Yeol, Seo, Jin-Ho, Park, Jin Hwan, Koo, Hyun Min, Cho, Kwang Myung, Park, Jin-Byung, Ha, Suk-Jin, Kweon, Dae-Hyuk
Format:	Artikel
Sprache:	eng
Schlagworte:	AtoB Bacteria Biotechnology Caproates - analysis Caproates - metabolism Chains Construction Ethanol - metabolism Fermentation Galactose - metabolism Genes Glucose - metabolism Hexanoic acid Kluyveromyces - genetics Kluyveromyces - metabolism Kluyveromyces marxianus MCT1 Metabolic Engineering - methods Metabolic Networks and Pathways Pathways Saccharomyces cerevisiae Strain TES1 Yeast
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