Evaluation of PCL/GE-Based Electrospun Nanofibers for Tissue Engineering and Drug Delivery Application
Scaffold provides a suitable medium for cell growing and drug delivery while enhancing the cell transplantation efficiency. In this project, nanofibrous scaffolds were fabricated through electrospinning of Polycaprolactone (PCL) and Gelatin (GE). Processing parameters and solution parameters were op...
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| Veröffentlicht in: | Applied Mechanics and Materials 2014-11, Vol.695 (Advanced Research in Materials and Engineering Applications), p.332-335 |
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| container_issue | Advanced Research in Materials and Engineering Applications |
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| creator | Lim, Mim Mim Sultana, Naznin Chong, Lor Huai |
| description | Scaffold provides a suitable medium for cell growing and drug delivery while enhancing the cell transplantation efficiency. In this project, nanofibrous scaffolds were fabricated through electrospinning of Polycaprolactone (PCL) and Gelatin (GE). Processing parameters and solution parameters were optimized to achieve the desired properties of PCL/GE nanofibers. Scanning Electron Microscopy (SEM), water contact angle and Attenuated Total Reflectance–Fourier Transformed Infrared Spectroscopy (ATR-FTIR) were implemented to characterize the fabricated nanofibers. It was found that 14% w/v PCL/GE shows the best fibers’ diameter, pore size, contact angle and less bead formation. This sample is suitable to be further investigated for the application of tissue engineering (TE) and drug delivery system (DDS). |
| doi_str_mv | 10.4028/www.scientific.net/AMM.695.332 |
| format | Article |
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| ispartof | Applied Mechanics and Materials, 2014-11, Vol.695 (Advanced Research in Materials and Engineering Applications), p.332-335 |
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| language | eng |
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| source | Scientific.net Journals |
| subjects | Beads Contact angle Drug delivery systems Electrospinning Nanofibers Scaffolds Scanning electron microscopy Tissue engineering |
| title | Evaluation of PCL/GE-Based Electrospun Nanofibers for Tissue Engineering and Drug Delivery Application |
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