Anti-tumour activity of phosphoinositide-3-kinase antagonist AEZS-126 in models of ovarian cancer

Purpose Platinum resistance is the most crucial problem for treatment of ovarian cancer. There is a clinical need for new treatment strategies which overcome platinum resistance. Recently high level of AKT was shown to be involved in platinum resistance and furthermore in resistance against Natural-...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of gynecology and obstetrics 2015, Vol.291 (1), p.131-141
Hauptverfasser:	Hahne, Jens C., Kurz, Antje, Meyer, Susanne R., Dietl, Johannes, Engel, Jörg B., Honig, Arnd
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Apoptosis - drug effects Cell Line, Tumor Cytotoxicity Endocrinology Female Gynecologic Oncology Gynecology Human Genetics Humans Imidazoles - pharmacology Indoles - pharmacology Medicine Medicine & Public Health Obstetrics/Perinatology/Midwifery Ovarian cancer Ovarian Neoplasms - drug therapy Ovarian Neoplasms - pathology Phosphatidylinositol 3-Kinases - antagonists & inhibitors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!