Influence of HLA-DRB alleles on haemorrhagic fever with renal syndrome in a Chinese Han population in Hubei Province, China

Specific human leucocyte antigen (HLA) alleles are considered a genetic risk factor for the progression of haemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses. The aim of this study was to establish whether HLA-DRB alleles are associated with the severity of HFRS caused by different...

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Veröffentlicht in:	European journal of clinical microbiology & infectious diseases 2015-01, Vol.34 (1), p.187-195
Hauptverfasser:	Zhu, N., Luo, F., Chen, Q., Li, N., Xiong, H., Feng, Y., Yang, Z., Hou, W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Alleles Antigens Biomedical and Life Sciences Biomedicine China Disease Disease Susceptibility Female Fever Gene Frequency Hantaan virus - immunology Hantaan virus - isolation & purification Hantavirus Health care Hemorrhagic Fever with Renal Syndrome - genetics Hemorrhagic Fever with Renal Syndrome - pathology HLA-DR beta-Chains - genetics Humans Infections Internal Medicine Laboratories Leukocytes Male Medical Microbiology Middle Aged Patients Polymerase Chain Reaction Risk factors Seoul virus - immunology Seoul virus - isolation & purification Severity of Illness Index Virology Young Adult
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