Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices

Specific side-by-side interactions between transmembrane alpha-helices may be important in the assembly and function of integral membrane proteins. We describe a system for the genetic and biophysical analysis of these interactions. The transmembrane alpha-helical domain of interest is fused to the...

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Veröffentlicht in:The Journal of biological chemistry 1992-04, Vol.267 (11), p.7683-7689
Hauptverfasser: LEMMON, M. A, FLANAGAN, J. M, HUNT, J. F, ADAIR, B. D, BORMANN, B.-J, DEMPSEY, C. E, ENGELMAN, D. M
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Sprache:eng
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