Inhibition of placental growth factor in renal cell carcinoma

Placental growth factor (PlGF) is up-regulated in major malignant diseases or following antiangiogenic therapy, although it is present in low levels under normal physiological conditions. TB403, a monoclonal antibody against PlGF, was investigated in clear cell renal cell carcinoma (ccRCC) xenograft...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Anticancer research 2015-01, Vol.35 (1), p.531-541
Hauptverfasser:	Bessho, Hideharu, Wong, Bernice, Huang, Dan, Siew, Ee Yan, Huang, Dachuan, Tan, Jing, Ong, Choon Kiat, Tan, Soo Yong, Matsumoto, Kazumasa, Iwamura, Masatsugu, Teh, Bin Tean
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - pharmacology Antibodies, Monoclonal - therapeutic use Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Carcinoma, Renal Cell - blood supply Carcinoma, Renal Cell - drug therapy Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - pathology Cell Line, Tumor Drug Resistance, Neoplasm Female Humans Indoles - pharmacology Kidney Neoplasms - blood supply Kidney Neoplasms - drug therapy Kidney Neoplasms - metabolism Kidney Neoplasms - pathology Mice, Nude Neovascularization, Pathologic - drug therapy Placenta Growth Factor Pregnancy Proteins - antagonists & inhibitors Pregnancy Proteins - blood Pyrroles - pharmacology Transcriptome - drug effects Tumor Burden - drug effects Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!