In vivo absorption of didanosine formulated in pellets composed of chitosan microspheres

The in vivo absorption of didanosine was studied, focusing on the performance of a novel pharmaceutical formulation for didanosine, composed of chitosan granules containing didanosine incorporated in chitosan microspheres. This novel formulation is aimed at oral administration in AIDS therapy. The e...

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Veröffentlicht in:	In vivo (Athens) 2014-11, Vol.28 (6), p.1045-1050
Hauptverfasser:	Severino, Patrícia, Da Silva, Classius Ferreira, Dalla Costa, Teresa Cristina T, Silva, Heloisa, Chaud, Marco V, Santana, Maria Helena A, Souto, Eliana B
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption, Physiological Animals Anti-HIV Agents - chemistry Anti-HIV Agents - pharmacokinetics Chemistry, Pharmaceutical Chitosan - chemistry Didanosine - chemistry Didanosine - pharmacokinetics Dogs Male Microspheres Tablets
Online-Zugang:	Volltext
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