Wall-eyed bilateral internuclear ophthalmoplegia: review of pathogenesis, diagnosis, prognosis and management
Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is an uncommon disorder of ocular motility that possesses a unique spectrum of clinical findings, consisting of primary gaze exotropia, adduction impairment and nystagmus of the abducting eye. WEBINO is a variant of internuclear ophthalmopleg...
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| Veröffentlicht in: | Clinical and experimental optometry 2015-01, Vol.98 (1), p.25-30 |
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| creator | Wu, Yu-tai Cafiero-chin, Malinda Marques, Cathy |
| description | Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is an uncommon disorder of ocular motility that possesses a unique spectrum of clinical findings, consisting of primary gaze exotropia, adduction impairment and nystagmus of the abducting eye. WEBINO is a variant of internuclear ophthalmoplegia (INO) sharing similar pathophysiology and aetiologies. Much of the literature published on internuclear ophthalmoplegia and its variants focuses on aetiology and pathophysiology, whereas there has been less information addressing prognosis and management. This review will provide current perspectives on the pathogenesis, prognosis and management of WEBINO syndrome. |
| doi_str_mv | 10.1111/cxo.12200 |
| format | Article |
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WEBINO is a variant of internuclear ophthalmoplegia (INO) sharing similar pathophysiology and aetiologies. Much of the literature published on internuclear ophthalmoplegia and its variants focuses on aetiology and pathophysiology, whereas there has been less information addressing prognosis and management. This review will provide current perspectives on the pathogenesis, prognosis and management of WEBINO syndrome.</description><identifier>ISSN: 0816-4622</identifier><identifier>EISSN: 1444-0938</identifier><identifier>DOI: 10.1111/cxo.12200</identifier><identifier>PMID: 25308307</identifier><language>eng</language><publisher>Australia: Taylor & Francis</publisher><subject>abducens nucleus ; brainstem infarction ; Diagnostic Techniques, Ophthalmological ; diplopia ; Disease Management ; exotropia ; extraocular muscle surgery ; Eye Movements - physiology ; Humans ; internuclear ophthalmoplegia ; medial longitudinal fasciculus ; multiple sclerosis ; nystagmus ; ocular motility ; Ocular Motility Disorders - diagnosis ; Ocular Motility Disorders - physiopathology ; Ocular Motility Disorders - therapy ; paramedian pontine reticular formation ; Prognosis</subject><ispartof>Clinical and experimental optometry, 2015-01, Vol.98 (1), p.25-30</ispartof><rights>2014 The Authors. Clinical and Experimental Optometry © 2014 Optometry Australia 2014</rights><rights>2014 The Authors. Clinical and Experimental Optometry © 2014 Optometrists Association Australia</rights><rights>2014 The Authors. 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WEBINO is a variant of internuclear ophthalmoplegia (INO) sharing similar pathophysiology and aetiologies. Much of the literature published on internuclear ophthalmoplegia and its variants focuses on aetiology and pathophysiology, whereas there has been less information addressing prognosis and management. This review will provide current perspectives on the pathogenesis, prognosis and management of WEBINO syndrome.</description><subject>abducens nucleus</subject><subject>brainstem infarction</subject><subject>Diagnostic Techniques, Ophthalmological</subject><subject>diplopia</subject><subject>Disease Management</subject><subject>exotropia</subject><subject>extraocular muscle surgery</subject><subject>Eye Movements - physiology</subject><subject>Humans</subject><subject>internuclear ophthalmoplegia</subject><subject>medial longitudinal fasciculus</subject><subject>multiple sclerosis</subject><subject>nystagmus</subject><subject>ocular motility</subject><subject>Ocular Motility Disorders - diagnosis</subject><subject>Ocular Motility Disorders - physiopathology</subject><subject>Ocular Motility Disorders - therapy</subject><subject>paramedian pontine reticular formation</subject><subject>Prognosis</subject><issn>0816-4622</issn><issn>1444-0938</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kEtvFDEQhC0EIpvAgT-AfASJSfyaFze0goAUKRcQ3Kweu71r5LEHe5Zl_z1DJuGC6EvV4etSqQh5wdklX-7K_EqXXAjGHpENV0pVrJfdY7JhHW8q1QhxRs5L-c6YULJXT8mZqCXrJGs3ZPwKIVR4QksHH2DGDIH6uGg8mICQaZr28x7CmKaAOw9vacafHo80OTrBvE87jFh8eUOth11Md3bKabUUoqUjRNjhiHF-Rp44CAWf3-sF-fLh_eftx-rm9vrT9t1NZRSrWdUzZBKgs6AGxgFVq7BBY2vhXOdk39uWIW_kYNoWhtbUSlmHUvEGDMDA5QV5teYuRX4csMx69MVgCBAxHYrmjeKCCdbXC_p6RU1OpWR0esp-hHzSnOk_6-plXX237sK-vI89DCPav-TDnAtwtQJHH_D0_yS9_Xb7EKnWDx9dyiMcUw5Wz3AKKbsM0fii5b9NfgM3zZiP</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Wu, Yu-tai</creator><creator>Cafiero-chin, Malinda</creator><creator>Marques, Cathy</creator><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150101</creationdate><title>Wall-eyed bilateral internuclear ophthalmoplegia: review of pathogenesis, diagnosis, prognosis and management</title><author>Wu, Yu-tai ; Cafiero-chin, Malinda ; Marques, Cathy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4050-90e03aa8da4b01ae474e6ecd52ff8f399d70e163bc77ab7c544dfe3416acaab13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>abducens nucleus</topic><topic>brainstem infarction</topic><topic>Diagnostic Techniques, Ophthalmological</topic><topic>diplopia</topic><topic>Disease Management</topic><topic>exotropia</topic><topic>extraocular muscle surgery</topic><topic>Eye Movements - physiology</topic><topic>Humans</topic><topic>internuclear ophthalmoplegia</topic><topic>medial longitudinal fasciculus</topic><topic>multiple sclerosis</topic><topic>nystagmus</topic><topic>ocular motility</topic><topic>Ocular Motility Disorders - diagnosis</topic><topic>Ocular Motility Disorders - physiopathology</topic><topic>Ocular Motility Disorders - therapy</topic><topic>paramedian pontine reticular formation</topic><topic>Prognosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wu, Yu-tai</creatorcontrib><creatorcontrib>Cafiero-chin, Malinda</creatorcontrib><creatorcontrib>Marques, Cathy</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental optometry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wu, Yu-tai</au><au>Cafiero-chin, Malinda</au><au>Marques, Cathy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Wall-eyed bilateral internuclear ophthalmoplegia: review of pathogenesis, diagnosis, prognosis and management</atitle><jtitle>Clinical and experimental optometry</jtitle><addtitle>Clin Exp Optom</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>98</volume><issue>1</issue><spage>25</spage><epage>30</epage><pages>25-30</pages><issn>0816-4622</issn><eissn>1444-0938</eissn><abstract>Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is an uncommon disorder of ocular motility that possesses a unique spectrum of clinical findings, consisting of primary gaze exotropia, adduction impairment and nystagmus of the abducting eye. 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| ispartof | Clinical and experimental optometry, 2015-01, Vol.98 (1), p.25-30 |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wiley Online Library All Journals; Alma/SFX Local Collection |
| subjects | abducens nucleus brainstem infarction Diagnostic Techniques, Ophthalmological diplopia Disease Management exotropia extraocular muscle surgery Eye Movements - physiology Humans internuclear ophthalmoplegia medial longitudinal fasciculus multiple sclerosis nystagmus ocular motility Ocular Motility Disorders - diagnosis Ocular Motility Disorders - physiopathology Ocular Motility Disorders - therapy paramedian pontine reticular formation Prognosis |
| title | Wall-eyed bilateral internuclear ophthalmoplegia: review of pathogenesis, diagnosis, prognosis and management |
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