Seroprevalence of HTLV-I and HTLV-II among Intravenous Drug Users and Persons in Clinics for Sexually Transmitted Diseases
HUMAN T-cell lymphotropic viruses Type I (HTLV-I) and Type II (HTLV-II) are closely related retroviruses. 1 HTLV-I is associated with adult T-cell leukemia and with myelopathy or tropical spastic paraparesis. 2 HTLV-II, first isolated from a patient with a variant of hairy-cell leukemia, has not bee...
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| Veröffentlicht in: | The New England journal of medicine 1992-02, Vol.326 (6), p.375-380 |
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| container_title | The New England journal of medicine |
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| creator | Khabbaz, Rima F Onorato, Ida M Cannon, Robert O Hartley, Trudie M Roberts, Beverly Hosein, Barbara Kaplan, Jonathan E |
| description | HUMAN T-cell lymphotropic viruses Type I (HTLV-I) and Type II (HTLV-II) are closely related retroviruses.
1
HTLV-I is associated with adult T-cell leukemia and with myelopathy or tropical spastic paraparesis.
2
HTLV-II, first isolated from a patient with a variant of hairy-cell leukemia, has not been consistently associated with any specific disease. Seroreactivity to HTLV has been well documented among intravenous drug users in several major U.S. metropolitan areas.
3
,
4
Reported seroprevalence rates in intravenous drug users have ranged from 2 percent to 49 percent. These rates are difficult to compare, however, because of differences in study design, in sampling schemes, in the . . . |
| doi_str_mv | 10.1056/NEJM199202063260604 |
| format | Article |
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1
HTLV-I is associated with adult T-cell leukemia and with myelopathy or tropical spastic paraparesis.
2
HTLV-II, first isolated from a patient with a variant of hairy-cell leukemia, has not been consistently associated with any specific disease. Seroreactivity to HTLV has been well documented among intravenous drug users in several major U.S. metropolitan areas.
3
,
4
Reported seroprevalence rates in intravenous drug users have ranged from 2 percent to 49 percent. These rates are difficult to compare, however, because of differences in study design, in sampling schemes, in the . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199202063260604</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston: Massachusetts Medical Society</publisher><subject>Central nervous system diseases ; Clinics ; Drug abuse ; Enzyme-linked immunosorbent assay ; Heroin ; HIV ; Human immunodeficiency virus ; Intravenous administration ; Leukemia ; Lymphocytes T ; Medical tests ; Peptides ; Serology ; Sexually transmitted diseases ; Spinal cord ; STD</subject><ispartof>The New England journal of medicine, 1992-02, Vol.326 (6), p.375-380</ispartof><rights>Copyright Massachusetts Medical Society Feb 6, 1992</rights><rights>Copyright Massachusetts Medical Society, Publishing Division Feb 6, 1992</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c480t-ff68388a4274b87930d9568bc3467461f0add987b160a882e165fa0d7a5ba43c3</citedby><cites>FETCH-LOGICAL-c480t-ff68388a4274b87930d9568bc3467461f0add987b160a882e165fa0d7a5ba43c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199202063260604$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1983445373?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064,64385,64387,64389,72469</link.rule.ids></links><search><creatorcontrib>Khabbaz, Rima F</creatorcontrib><creatorcontrib>Onorato, Ida M</creatorcontrib><creatorcontrib>Cannon, Robert O</creatorcontrib><creatorcontrib>Hartley, Trudie M</creatorcontrib><creatorcontrib>Roberts, Beverly</creatorcontrib><creatorcontrib>Hosein, Barbara</creatorcontrib><creatorcontrib>Kaplan, Jonathan E</creatorcontrib><title>Seroprevalence of HTLV-I and HTLV-II among Intravenous Drug Users and Persons in Clinics for Sexually Transmitted Diseases</title><title>The New England journal of medicine</title><description>HUMAN T-cell lymphotropic viruses Type I (HTLV-I) and Type II (HTLV-II) are closely related retroviruses.
1
HTLV-I is associated with adult T-cell leukemia and with myelopathy or tropical spastic paraparesis.
2
HTLV-II, first isolated from a patient with a variant of hairy-cell leukemia, has not been consistently associated with any specific disease. Seroreactivity to HTLV has been well documented among intravenous drug users in several major U.S. metropolitan areas.
3
,
4
Reported seroprevalence rates in intravenous drug users have ranged from 2 percent to 49 percent. These rates are difficult to compare, however, because of differences in study design, in sampling schemes, in the . . .</description><subject>Central nervous system diseases</subject><subject>Clinics</subject><subject>Drug abuse</subject><subject>Enzyme-linked immunosorbent assay</subject><subject>Heroin</subject><subject>HIV</subject><subject>Human immunodeficiency virus</subject><subject>Intravenous administration</subject><subject>Leukemia</subject><subject>Lymphocytes T</subject><subject>Medical tests</subject><subject>Peptides</subject><subject>Serology</subject><subject>Sexually transmitted diseases</subject><subject>Spinal cord</subject><subject>STD</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kU9v1DAQxS1EJZaWT8DFAolLFRj_iWMf0ba0i7YFqVuukTeZVFkl9uJJKsqnr2F7QsBc5h1-bzRPj7HXAt4LKM2H6_PPV8I5CRKMkgYM6GdsIUqlCq3BPGcLAGkLXTn1gr0k2kEeod2C_bzBFPcJ7_2AoUEeO365WX8rVtyH9klmPcZwx1dhSv4eQ5yJn6X5jt8SJvoNfs0iBuJ94MuhD31DvIuJ3-CP2Q_DA98kH2jspwlbftYTekI6YUedHwhfPe1jdvvpfLO8LNZfLlbLj-ui0RamouuMVdZ6LSu9tTkBtK40dtsobSptRAe-bZ2ttsKAt1aiMGXnoa18ufVaNeqYvTvc3af4fUaa6rGnBofBB8xRamE0VOAgg2_-AHdxTiH_VkupXKmtLDP09l-QcFZpXapKZUodqCZFooRdvU_96NNDLaD-VVn9l8qy6_TgGkeqA-7G_9KPtYCTaw</recordid><startdate>19920206</startdate><enddate>19920206</enddate><creator>Khabbaz, Rima F</creator><creator>Onorato, Ida M</creator><creator>Cannon, Robert O</creator><creator>Hartley, Trudie M</creator><creator>Roberts, Beverly</creator><creator>Hosein, Barbara</creator><creator>Kaplan, Jonathan E</creator><general>Massachusetts Medical Society</general><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7U9</scope><scope>H94</scope></search><sort><creationdate>19920206</creationdate><title>Seroprevalence of HTLV-I and HTLV-II among Intravenous Drug Users and Persons in Clinics for Sexually Transmitted Diseases</title><author>Khabbaz, Rima F ; 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1
HTLV-I is associated with adult T-cell leukemia and with myelopathy or tropical spastic paraparesis.
2
HTLV-II, first isolated from a patient with a variant of hairy-cell leukemia, has not been consistently associated with any specific disease. Seroreactivity to HTLV has been well documented among intravenous drug users in several major U.S. metropolitan areas.
3
,
4
Reported seroprevalence rates in intravenous drug users have ranged from 2 percent to 49 percent. These rates are difficult to compare, however, because of differences in study design, in sampling schemes, in the . . .</abstract><cop>Boston</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJM199202063260604</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Central nervous system diseases Clinics Drug abuse Enzyme-linked immunosorbent assay Heroin HIV Human immunodeficiency virus Intravenous administration Leukemia Lymphocytes T Medical tests Peptides Serology Sexually transmitted diseases Spinal cord STD |
| title | Seroprevalence of HTLV-I and HTLV-II among Intravenous Drug Users and Persons in Clinics for Sexually Transmitted Diseases |
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