Estrogen modulates intestinal mucus physiochemical properties and protects against oxidant injury

The intestinal epithelial barrier and the intestinal mucus layer may be protective against trauma/hemorrhage shock-induced injury in females. This effect is related to estradiol (E₂) concentrations and varies with the menstrual cycle. We examined the ability of E₂ to impact the physiochemical proper...

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Veröffentlicht in:	The journal of trauma and acute care surgery 2015-01, Vol.78 (1), p.94-99
Hauptverfasser:	Diebel, Mark E, Diebel, Lawrence N, Manke, Charles W, Liberati, David M
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Elasticity Enzyme-Linked Immunosorbent Assay Estradiol - pharmacology Female HT29 Cells Humans Hydrogen Peroxide - pharmacology In Vitro Techniques Intestinal Mucosa - metabolism Intestines - cytology Malondialdehyde - metabolism Mucus - chemistry Mucus - drug effects Oxidative Stress Permeability Protein Carbonylation Viscosity
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