Novel mechanism of intracellular calcium release in pituitary cells

In sea urchin eggs an enzymatic metabolite of beta-NAD+, called cyclic ADP-ribose (cADPR), is as potent and powerful a releaser of sequestered intracellular Ca2+ as is inositol 1,4,5-trisphosphate (IP3). The enzyme that synthesizes cADPR is present in several vertebrate animal tissues, but the Ca(2+...

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Veröffentlicht in:	The Journal of biological chemistry 1991-09, Vol.266 (26), p.16985-16988
Hauptverfasser:	H Koshiyama, H C Lee, A H Tashjian, Jr
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate Ribose - metabolism Animals Biological and medical sciences calcium Calcium - metabolism Cell Line Cell Membrane Permeability Cell physiology Cyclic ADP-Ribose Fundamental and applied biological sciences. Psychology Inositol 1,4,5-Trisphosphate - metabolism intracellular mediation Membrane and intracellular transports Molecular and cellular biology NAD - metabolism pituitary Pituitary Gland - cytology Pituitary Gland - metabolism Rats Rats, Inbred Strains release Second Messenger Systems
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