Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) alterations to colorectal cancer susceptibility: a case–control study

Cyclin D1 ( CCND1 ) and E-cadherin ( CDH1 ) are two important genes of the β-catenin/LEF pathway that is involved in tumorigenesis of various cancers including colorectal cancer (CRC). However, studies of the association between genetic variants of these two genes and CRC have shown conflicting resu...

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Veröffentlicht in:	Tumor biology 2014-12, Vol.35 (12), p.12059-12067
Hauptverfasser:	Govatati, Suresh, Singamsetty, Gopi Krishna, Nallabelli, Nayudu, Malempati, Sravanthi, Rao, Pasupuleti Sreenivasa, Madamchetty, Venkata Kranthi Kumar, Govatati, Sowdamani, Kanapuram, Rudramadevi, Narayana, Nagesh, Bhanoori, Manjula, Kassetty, Kondaiah, Nallanchakravarthula, Varadacharyulu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Biological variation Biomedicine Cadherins - genetics Cancer Research Case-Control Studies Colorectal cancer Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Cyclin D1 - genetics Female Genes Genetic Predisposition to Disease Genetic Variation Genotype Haplotypes Humans India Linkage Disequilibrium Male Medical prognosis Middle Aged Neoplasm Invasiveness Neoplasm Staging Polymorphism Polymorphism, Single Nucleotide Research Article Risk Factors Sequence Analysis, DNA Tumorigenesis
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