MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects
Objective In this study we aimed to describe the magnetic resonance imaging (MRI) pattern of the distribution of bone marrow edema (BME) and joint erosion in hands and wrists of patients with systemic lupus erythematosus (SLE) with arthritis in comparison with rheumatoid arthritis (RA) and healthy s...
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| Veröffentlicht in: | Skeletal radiology 2015-02, Vol.44 (2), p.261-266 |
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| creator | Chiara, Tani Dario, D’aniello Niccolò, Possemato Andrea, Delle Sedie Davide, Caramella Stefano, Bombardieri Marta, Mosca |
| description | Objective
In this study we aimed to describe the magnetic resonance imaging (MRI) pattern of the distribution of bone marrow edema (BME) and joint erosion in hands and wrists of patients with systemic lupus erythematosus (SLE) with arthritis in comparison with rheumatoid arthritis (RA) and healthy subjects (H).
Methods
SLE patients with arthritis (
n
= 50), patients with RA (
n
= 22), and H (
n
= 48) were enrolled. Every patient underwent a non-dominant hand (2nd–5th metacarpophalangeal joints) and wrist MRI without contrast injection with a low-field extremity dedicated 0.2-Tesla instrument.
Results
BME was observed in two SLE patients in the hand (4 %) and in 15 in the wrist (13 %) versus three (30 %), and 14 (63 %) RA patients. No BME was found in H. Erosions were observed in the hand in 24 SLE patients (48 %), 15 RA patients (68 %), and 9 H (18 %); in the wrist, in 41 (82 %) SLE, all RA and 47 (97 %) H. The cumulative erosive burden in SLE was significantly higher than in H (
c
= 0.002) but similar to RA patients.
Conclusions
Joint involvement of the wrist in SLE is similar to RA and is not as rare as expected, as shown by the comparison with healthy subjects. On the contrary, the involvement of the hand in SLE is significantly lower compared to RA. |
| doi_str_mv | 10.1007/s00256-014-2033-0 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1640482780</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A731034667</galeid><sourcerecordid>A731034667</sourcerecordid><originalsourceid>FETCH-LOGICAL-c564t-d4fc42c11dd448b33fabc30070db38732b0b9a10fe2e907c29e97284652a69273</originalsourceid><addsrcrecordid>eNp1kUuLFTEQhYMoznX0B7iRgBs3PVYenXS7GwYfAyOC6Dqk09XTufTjmqRHGvzxprmjXEXJIpD66tRJHUKeM7hgAPp1BOClKoDJgoMQBTwgOyYFLzhT7CHZgVC5ImR1Rp7EuAdgWpfqMTnjpZCshHJHfnz8fE0PNiUME507akPqg08-Uj_RuMaEo3d0WA5LpBjW1ONo0xyX-IZa6ubxYINN_g5pTEu70u8-9TT0uGyUb0_k7NTSHu2Q-pXGpdmjS_EpedTZIeKz-_ucfH339svVh-Lm0_vrq8ubwpVKpqKVnZPcMda2UlaNEJ1tnMgLgLYRlRa8gaa2DDrkWIN2vMZa80qqkltVcy3Oyauj7iHM3xaMyYw-OhwGO-G8RMOUBFlxXUFGX_6F7uclTNldpkRdacXLE-rWDmj81M0pWLeJmkstGAip1Db24h9UPu221HnCzuf3PxrYscGFOcaAnTkEP9qwGgZmS9wcEzc5cbMlbjYrL-4NL82I7e-OXxFngB-BmEvTLYaTH_1X9Sdj57W0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1639876250</pqid></control><display><type>article</type><title>MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Chiara, Tani ; Dario, D’aniello ; Niccolò, Possemato ; Andrea, Delle Sedie ; Davide, Caramella ; Stefano, Bombardieri ; Marta, Mosca</creator><creatorcontrib>Chiara, Tani ; Dario, D’aniello ; Niccolò, Possemato ; Andrea, Delle Sedie ; Davide, Caramella ; Stefano, Bombardieri ; Marta, Mosca</creatorcontrib><description>Objective
In this study we aimed to describe the magnetic resonance imaging (MRI) pattern of the distribution of bone marrow edema (BME) and joint erosion in hands and wrists of patients with systemic lupus erythematosus (SLE) with arthritis in comparison with rheumatoid arthritis (RA) and healthy subjects (H).
Methods
SLE patients with arthritis (
n
= 50), patients with RA (
n
= 22), and H (
n
= 48) were enrolled. Every patient underwent a non-dominant hand (2nd–5th metacarpophalangeal joints) and wrist MRI without contrast injection with a low-field extremity dedicated 0.2-Tesla instrument.
Results
BME was observed in two SLE patients in the hand (4 %) and in 15 in the wrist (13 %) versus three (30 %), and 14 (63 %) RA patients. No BME was found in H. Erosions were observed in the hand in 24 SLE patients (48 %), 15 RA patients (68 %), and 9 H (18 %); in the wrist, in 41 (82 %) SLE, all RA and 47 (97 %) H. The cumulative erosive burden in SLE was significantly higher than in H (
c
= 0.002) but similar to RA patients.
Conclusions
Joint involvement of the wrist in SLE is similar to RA and is not as rare as expected, as shown by the comparison with healthy subjects. On the contrary, the involvement of the hand in SLE is significantly lower compared to RA.</description><identifier>ISSN: 0364-2348</identifier><identifier>EISSN: 1432-2161</identifier><identifier>DOI: 10.1007/s00256-014-2033-0</identifier><identifier>PMID: 25341505</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Arthritis ; Arthritis - etiology ; Arthritis - pathology ; Bone Marrow - pathology ; Comparative analysis ; Female ; Finger Joint - pathology ; Humans ; Imaging ; Lupus Erythematosus, Systemic - complications ; Lupus Erythematosus, Systemic - pathology ; Magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Nuclear Medicine ; Observer Variation ; Orthopedics ; Pathology ; Radiology ; Reference Values ; Reproducibility of Results ; Rheumatoid factor ; Scientific Article ; Sensitivity and Specificity ; Systemic lupus erythematosus ; Wrist Joint - pathology</subject><ispartof>Skeletal radiology, 2015-02, Vol.44 (2), p.261-266</ispartof><rights>ISS 2014</rights><rights>COPYRIGHT 2015 Springer</rights><rights>ISS 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c564t-d4fc42c11dd448b33fabc30070db38732b0b9a10fe2e907c29e97284652a69273</citedby><cites>FETCH-LOGICAL-c564t-d4fc42c11dd448b33fabc30070db38732b0b9a10fe2e907c29e97284652a69273</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00256-014-2033-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00256-014-2033-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,778,782,27911,27912,41475,42544,51306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25341505$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chiara, Tani</creatorcontrib><creatorcontrib>Dario, D’aniello</creatorcontrib><creatorcontrib>Niccolò, Possemato</creatorcontrib><creatorcontrib>Andrea, Delle Sedie</creatorcontrib><creatorcontrib>Davide, Caramella</creatorcontrib><creatorcontrib>Stefano, Bombardieri</creatorcontrib><creatorcontrib>Marta, Mosca</creatorcontrib><title>MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects</title><title>Skeletal radiology</title><addtitle>Skeletal Radiol</addtitle><addtitle>Skeletal Radiol</addtitle><description>Objective
In this study we aimed to describe the magnetic resonance imaging (MRI) pattern of the distribution of bone marrow edema (BME) and joint erosion in hands and wrists of patients with systemic lupus erythematosus (SLE) with arthritis in comparison with rheumatoid arthritis (RA) and healthy subjects (H).
Methods
SLE patients with arthritis (
n
= 50), patients with RA (
n
= 22), and H (
n
= 48) were enrolled. Every patient underwent a non-dominant hand (2nd–5th metacarpophalangeal joints) and wrist MRI without contrast injection with a low-field extremity dedicated 0.2-Tesla instrument.
Results
BME was observed in two SLE patients in the hand (4 %) and in 15 in the wrist (13 %) versus three (30 %), and 14 (63 %) RA patients. No BME was found in H. Erosions were observed in the hand in 24 SLE patients (48 %), 15 RA patients (68 %), and 9 H (18 %); in the wrist, in 41 (82 %) SLE, all RA and 47 (97 %) H. The cumulative erosive burden in SLE was significantly higher than in H (
c
= 0.002) but similar to RA patients.
Conclusions
Joint involvement of the wrist in SLE is similar to RA and is not as rare as expected, as shown by the comparison with healthy subjects. On the contrary, the involvement of the hand in SLE is significantly lower compared to RA.</description><subject>Adult</subject><subject>Arthritis</subject><subject>Arthritis - etiology</subject><subject>Arthritis - pathology</subject><subject>Bone Marrow - pathology</subject><subject>Comparative analysis</subject><subject>Female</subject><subject>Finger Joint - pathology</subject><subject>Humans</subject><subject>Imaging</subject><subject>Lupus Erythematosus, Systemic - complications</subject><subject>Lupus Erythematosus, Systemic - pathology</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nuclear Medicine</subject><subject>Observer Variation</subject><subject>Orthopedics</subject><subject>Pathology</subject><subject>Radiology</subject><subject>Reference Values</subject><subject>Reproducibility of Results</subject><subject>Rheumatoid factor</subject><subject>Scientific Article</subject><subject>Sensitivity and Specificity</subject><subject>Systemic lupus erythematosus</subject><subject>Wrist Joint - pathology</subject><issn>0364-2348</issn><issn>1432-2161</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kUuLFTEQhYMoznX0B7iRgBs3PVYenXS7GwYfAyOC6Dqk09XTufTjmqRHGvzxprmjXEXJIpD66tRJHUKeM7hgAPp1BOClKoDJgoMQBTwgOyYFLzhT7CHZgVC5ImR1Rp7EuAdgWpfqMTnjpZCshHJHfnz8fE0PNiUME507akPqg08-Uj_RuMaEo3d0WA5LpBjW1ONo0xyX-IZa6ubxYINN_g5pTEu70u8-9TT0uGyUb0_k7NTSHu2Q-pXGpdmjS_EpedTZIeKz-_ucfH339svVh-Lm0_vrq8ubwpVKpqKVnZPcMda2UlaNEJ1tnMgLgLYRlRa8gaa2DDrkWIN2vMZa80qqkltVcy3Oyauj7iHM3xaMyYw-OhwGO-G8RMOUBFlxXUFGX_6F7uclTNldpkRdacXLE-rWDmj81M0pWLeJmkstGAip1Db24h9UPu221HnCzuf3PxrYscGFOcaAnTkEP9qwGgZmS9wcEzc5cbMlbjYrL-4NL82I7e-OXxFngB-BmEvTLYaTH_1X9Sdj57W0</recordid><startdate>20150201</startdate><enddate>20150201</enddate><creator>Chiara, Tani</creator><creator>Dario, D’aniello</creator><creator>Niccolò, Possemato</creator><creator>Andrea, Delle Sedie</creator><creator>Davide, Caramella</creator><creator>Stefano, Bombardieri</creator><creator>Marta, Mosca</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20150201</creationdate><title>MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects</title><author>Chiara, Tani ; Dario, D’aniello ; Niccolò, Possemato ; Andrea, Delle Sedie ; Davide, Caramella ; Stefano, Bombardieri ; Marta, Mosca</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c564t-d4fc42c11dd448b33fabc30070db38732b0b9a10fe2e907c29e97284652a69273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Arthritis</topic><topic>Arthritis - etiology</topic><topic>Arthritis - pathology</topic><topic>Bone Marrow - pathology</topic><topic>Comparative analysis</topic><topic>Female</topic><topic>Finger Joint - pathology</topic><topic>Humans</topic><topic>Imaging</topic><topic>Lupus Erythematosus, Systemic - complications</topic><topic>Lupus Erythematosus, Systemic - pathology</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nuclear Medicine</topic><topic>Observer Variation</topic><topic>Orthopedics</topic><topic>Pathology</topic><topic>Radiology</topic><topic>Reference Values</topic><topic>Reproducibility of Results</topic><topic>Rheumatoid factor</topic><topic>Scientific Article</topic><topic>Sensitivity and Specificity</topic><topic>Systemic lupus erythematosus</topic><topic>Wrist Joint - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chiara, Tani</creatorcontrib><creatorcontrib>Dario, D’aniello</creatorcontrib><creatorcontrib>Niccolò, Possemato</creatorcontrib><creatorcontrib>Andrea, Delle Sedie</creatorcontrib><creatorcontrib>Davide, Caramella</creatorcontrib><creatorcontrib>Stefano, Bombardieri</creatorcontrib><creatorcontrib>Marta, Mosca</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection (ProQuest)</collection><collection>Natural Science Collection (ProQuest)</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Skeletal radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chiara, Tani</au><au>Dario, D’aniello</au><au>Niccolò, Possemato</au><au>Andrea, Delle Sedie</au><au>Davide, Caramella</au><au>Stefano, Bombardieri</au><au>Marta, Mosca</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects</atitle><jtitle>Skeletal radiology</jtitle><stitle>Skeletal Radiol</stitle><addtitle>Skeletal Radiol</addtitle><date>2015-02-01</date><risdate>2015</risdate><volume>44</volume><issue>2</issue><spage>261</spage><epage>266</epage><pages>261-266</pages><issn>0364-2348</issn><eissn>1432-2161</eissn><abstract>Objective
In this study we aimed to describe the magnetic resonance imaging (MRI) pattern of the distribution of bone marrow edema (BME) and joint erosion in hands and wrists of patients with systemic lupus erythematosus (SLE) with arthritis in comparison with rheumatoid arthritis (RA) and healthy subjects (H).
Methods
SLE patients with arthritis (
n
= 50), patients with RA (
n
= 22), and H (
n
= 48) were enrolled. Every patient underwent a non-dominant hand (2nd–5th metacarpophalangeal joints) and wrist MRI without contrast injection with a low-field extremity dedicated 0.2-Tesla instrument.
Results
BME was observed in two SLE patients in the hand (4 %) and in 15 in the wrist (13 %) versus three (30 %), and 14 (63 %) RA patients. No BME was found in H. Erosions were observed in the hand in 24 SLE patients (48 %), 15 RA patients (68 %), and 9 H (18 %); in the wrist, in 41 (82 %) SLE, all RA and 47 (97 %) H. The cumulative erosive burden in SLE was significantly higher than in H (
c
= 0.002) but similar to RA patients.
Conclusions
Joint involvement of the wrist in SLE is similar to RA and is not as rare as expected, as shown by the comparison with healthy subjects. On the contrary, the involvement of the hand in SLE is significantly lower compared to RA.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>25341505</pmid><doi>10.1007/s00256-014-2033-0</doi><tpages>6</tpages></addata></record> |
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| ispartof | Skeletal radiology, 2015-02, Vol.44 (2), p.261-266 |
| issn | 0364-2348 1432-2161 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Arthritis Arthritis - etiology Arthritis - pathology Bone Marrow - pathology Comparative analysis Female Finger Joint - pathology Humans Imaging Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - pathology Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medicine Medicine & Public Health Middle Aged Nuclear Medicine Observer Variation Orthopedics Pathology Radiology Reference Values Reproducibility of Results Rheumatoid factor Scientific Article Sensitivity and Specificity Systemic lupus erythematosus Wrist Joint - pathology |
| title | MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects |
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