Histidine–Iridium(III) Coordination-Based Peptide Luminogenic Cyclization and Cyclo-RGD Peptides for Cancer-Cell Targeting

In the field of peptide drug discovery, structural constraining and fluorescent labeling are two sought-after techniques important for both basic research and pharmaceutical development. In this work, we describe an easy-to-use approach for simultaneous peptide cyclization and luminescent labeling b...

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Veröffentlicht in:	Journal of the American Chemical Society 2014-12, Vol.136 (51), p.17734-17737
Hauptverfasser:	Ma, Xiaochuan, Jia, Junli, Cao, Rui, Wang, Xiaobo, Fei, Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Cyclization Histidine - chemistry Humans Iridium - chemistry MCF-7 Cells Molecular Targeted Therapy Organometallic Compounds - chemistry Organometallic Compounds - pharmacology Peptides, Cyclic - chemistry Peptides, Cyclic - pharmacology
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