Automated Assignment of MS/MS Cleavable Cross-Links in Protein 3D-Structure Analysis

CID-MS/MS cleavable cross-linkers hold an enormous potential for an automated analysis of cross-linked products, which is essential for conducting structural proteomics studies. The created characteristic fragment ion patterns can easily be used for an automated assignment and discrimination of cros...

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Veröffentlicht in:	Journal of the American Society for Mass Spectrometry 2015-01, Vol.26 (1), p.83-97
Hauptverfasser:	Götze, Michael, Pettelkau, Jens, Fritzsche, Romy, Ihling, Christian H., Schäfer, Mathias, Sinz, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Automation Bioinformatics Biotechnology Chemistry Chemistry and Materials Science Cross-Linking Reagents Crosslinking Data analysis Graphical user interface Links Mass spectrometry Mathematical analysis Models, Molecular Organic Chemistry Proteins Proteins - chemistry Proteomics Research Article Sequence Analysis, Protein - methods Software Software development tools Structural analysis Tandem Mass Spectrometry - methods User-Computer Interface Workflow
Online-Zugang:	Volltext
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