Increased activity of MMP‐2 in hypertensive obese children is associated with hypoadiponectinemia

Objective To compare the circulating levels of MMP‐2 and TIMP‐2 and the MMP‐2/TIMP‐2 ratio in control, obese, and obese hypertensive children and adolescents and to assess whether hypoadiponectinemia is associated with MMP‐2 and TIMP‐2 levels and MMP‐2/TIMP‐2 ratios. Methods Studies were carried out...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2015-01, Vol.23 (1), p.177-182
Hauptverfasser:	Belo, Vanessa A., Lacchini, Riccardo, Miranda, Josiane A., Lanna, Carla M.M., Souza‐Costa, Debora C., Tanus‐Santos, Jose E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin - deficiency Adiponectin - metabolism Adolescent Atherosclerosis Bands Bioavailability Blood pressure Case-Control Studies Child Cross-Sectional Studies Diabetes Endocrinology Enzyme-Linked Immunosorbent Assay Enzymes Female Humans Hypertension Hypertension - complications Hypertension - metabolism Insulin Insulin resistance Male Matrix Metalloproteinase 2 - blood Matrix Metalloproteinase 2 - metabolism Metabolism, Inborn Errors - complications Metabolism, Inborn Errors - metabolism Obesity Pathogenesis Pediatric Obesity - complications Pediatric Obesity - metabolism Ratios Regression Analysis Teenagers Tissue Inhibitor of Metalloproteinase-2 - blood
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