In vitro and in vivo safety and efficacy studies of amphotericin B on Babesia gibsoni

•Amphotericin B exhibits in vitro activity against B. gibsoni.•Liposomal amphotericin B inhibited invasion of free parasites into erythrocytes.•Amphotericin B induced mild hemolysis of canine erythrocytes in vitro.•Amphotericin B has in vivo activity against B. gibsoni.•Amphotericin B affects kidney...

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Veröffentlicht in:	Veterinary parasitology 2014-10, Vol.205 (3-4), p.424-433
Hauptverfasser:	Yamasaki, Masahiro, Harada, Eriko, Tamura, Yu, Lim, Sue Yee, Ohsuga, Tatsuyuki, Yokoyama, Nozomu, Morishita, Keitaro, Nakamura, Kensuke, Ohta, Hiroshi, Takiguchi, Mitsuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B Amphotericin B - pharmacology Animals Anti-babesial drug Anti-Bacterial Agents - pharmacology Babesia - drug effects Babesia gibsoni Babesiosis - drug therapy Babesiosis - parasitology Dog Diseases - drug therapy Dog Diseases - parasitology Dogs Erythrocytes - parasitology Female Liposomal amphotericin B Male Parasitemia - veterinary
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