Immunological profile of resistance and susceptibility in naturally infected dogs by Leishmania infantum

•We performed a detailed investigation to identify immunobiomarkers of resistance and susceptibility in naturally infected dogs by Leishmania infantum.•Symptomatic dogs display lower circulating T and B lymphocytes with higher production of IFN-γ and IL-4 whereas asymptomatic dogs-I exhibit a cellul...

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Veröffentlicht in:	Veterinary parasitology 2014-10, Vol.205 (3-4), p.472-482
Hauptverfasser:	de Almeida Leal, Gleisiane Gomes, Roatt, Bruno Mendes, de Oliveira Aguiar-Soares, Rodrigo Dian, Carneiro, Cláudia Martins, Giunchetti, Rodolfo Cordeiro, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Francisco, Amanda Fortes, Cardoso, Jamille Mirelle, Mathias, Fernando Augusto Siqueira, Correa-Oliveira, Rodrigo, Carneiro, Mariângela, Coura-Vital, Wendel, Reis, Alexandre Barbosa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Protozoan - blood Biomarkers - metabolism Brazil - epidemiology Canine visceral leishmaniasis Clinical forms Cytokines Disease Resistance Disease Susceptibility Dog Diseases - parasitology Dogs Eosinophils - immunology Female Flow Cytometry - veterinary Immunophenotyping Leishmania infantum Leishmania infantum - immunology Leishmaniasis, Visceral - parasitology Leishmaniasis, Visceral - veterinary Male Monocytes - immunology T-Lymphocytes - immunology
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