Evaluation of the impact of quorum sensing transcriptional regulator SdiA on long-term persistence and fecal shedding of Escherichia coli O157:H7 in weaned calves

Escherichia coli O157:H7 (O157) colonization of bovine intestine is mediated through the locus of enterocyte effacement (LEE)-encoded type III secretion system and secreted virulence proteins that promote colonization of the recto-anal junction (RAJ) of the large intestine of cattle. The quorum sens...

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Veröffentlicht in:	Microbial pathogenesis 2013-04, Vol.57, p.21-26
Hauptverfasser:	Sharma, V.K., Bearson, S.M.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyl-Butyrolactones - pharmacology Animals bacterial adhesion Bacterial Adhesion - genetics bacterial colonization calves Cattle Cell Line cultured cells EHEC Escherichia coli Escherichia coli Infections - microbiology Escherichia coli O157 Escherichia coli O157 - genetics Escherichia coli O157 - pathogenicity Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism excretion feces Feces - microbiology Gene Deletion gene expression regulation Gene Expression Regulation, Bacterial - drug effects gene overexpression genes lactones large intestine LEE loci Male mutants mutation O157 Quorum sensing Quorum Sensing - genetics Trans-Activators - genetics Trans-Activators - metabolism transcription factors Type III secretion system Virulence Weaning
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