Enhanced external counterpulsation inhibits endothelial apoptosis via modulation of BIRC2 and Apaf-1 genes in porcine hypercholesterolemia

Abstract Objectives Enhanced external counterpulsation (EECP) could improve endothelium-dependent vasodilatation of carotid artery and restore imbalance of nitric oxide and endothein-1 in patients with coronary artery disease. Our study was designed to test the hypothesis that long-term EECP may pro...

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Veröffentlicht in:	International journal of cardiology 2014-02, Vol.171 (2), p.161-168
Hauptverfasser:	Xiong, Yan, Ren, Yu-feng, Xu, Jia, Yang, Da-ya, He, Xiao-hong, Luo, Jing-yun, Rana, Jamal S, Zhang, Yan, Zheng, Zhen-sheng, Liu, Dong-hong, Wu, Gui-fu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta, Abdominal - pathology Aorta, Abdominal - physiology Apoptosis Apoptosis - genetics Apoptotic Protease-Activating Factor 1 - genetics Atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiovascular Carotid Arteries - pathology Carotid Arteries - physiology Counterpulsation - methods Disease Models, Animal Disorders of blood lipids. Hyperlipoproteinemia Endothelial cell Endothelial Cells - pathology Endothelial Cells - physiology Enhanced external counterpulsation Gene Expression Regulation - physiology Heart Hypercholesterolemia - genetics Hypercholesterolemia - pathology Hypercholesterolemia - therapy Inhibitor of Apoptosis Proteins - genetics Male Medical sciences Metabolic diseases Random Allocation Sus scrofa Ubiquitin-Protein Ligases Vasodilation - physiology
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