Myocardin-A enhances expression of promyogenic genes without depressing telomerase activity in adipose tissue-derived mesenchymal stem cells

Abstract Background The stromal compartment of adult adipose tissue consists of mesenchymal stem cells (MSCs) characterized by co-expression of myocardin-A (McA) and telomerase reverse transcriptase (TERT). Objective This study aims at testing the growth and myogenic regenerative properties of adipo...

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Veröffentlicht in:	International journal of cardiology 2013-09, Vol.167 (6), p.2912-2921
Hauptverfasser:	Madonna, Rosalinda, Wu, Danli, Wassler, Michael, De Caterina, Raffaele, Willerson, James T, Geng, Yong-Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Adipose Tissue - metabolism Animals Biological and medical sciences Cardiology. Vascular system Cardiovascular Cells, Cultured Embryonic Stem Cells - metabolism Enzyme Activation - physiology Gene Expression Regulation Heart Male Medical sciences Mesenchymal cells Mesenchymal Stromal Cells - metabolism Mice Mice, Inbred BALB C Myocardin Myogenesis Stem cells Telomerase Telomerase - biosynthesis Telomerase - genetics Trans-Activators - biosynthesis Trans-Activators - genetics
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