Genes and Coronary Artery Disease: Where Are We?

Susceptibility to coronary artery disease (CAD) is claimed to be 40% to 60% inherited, but until recently genetic risk factors predisposing to CAD have been elusive. Comprehensive prevention of CAD requires manipulation of genetic risk. The availability of microarrays of single-nucleotide polymorphi...

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Veröffentlicht in:	Journal of the American College of Cardiology 2012-10, Vol.60 (18), p.1715-1721
Hauptverfasser:	ROBERTS, Robert, STEWART, Alexandre F. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cardiology - methods Cardiology - trends Cardiology. Vascular system Cholesterol, LDL - metabolism Chromosome Mapping Coronary Artery Disease - genetics Coronary heart disease Female Genetic Predisposition to Disease Genetic Variation Genome-Wide Association Study Heart Humans Male Medical sciences Middle Aged Myocardial Infarction - genetics Oligonucleotide Array Sequence Analysis - methods Phenotype Polymorphism, Single Nucleotide Risk Risk Factors
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