Profiles of activation, differentiation-markers, or β-integrins on T cells contribute to predict T cells' antileukemic responses after stimulation with leukemia-derived dendritic cells

Stem cell transplantations and donor lymphocyte infusions are promising immunotherapies to cure acute myeloid leukemia (AML). Leukemia-derived dendritic cells are known to improve antileukemic functionality of T cells. We evaluated the composition and development of distinct T-cell subtypes in AML p...

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Veröffentlicht in:	Journal of immunotherapy (1997) 2014-07, Vol.37 (6), p.331-347
Hauptverfasser:	Vogt, Valentin, Schick, Julia, Ansprenger, Christian, Braeu, Marion, Kroell, Tanja, Kraemer, Doris, Köhne, Claus-Henning, Hausmann, Andreas, Buhmann, Raymund, Tischer, Johanna, Schmetzer, Helga
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigen Presentation Antigens, Differentiation - metabolism Antigens, Neoplasm - immunology Cancer Vaccines Cells, Cultured Dendritic Cells - immunology Dendritic Cells - transplantation Female Humans Immunophenotyping Immunotherapy, Adoptive - methods Integrin beta Chains - metabolism Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - immunology Leukemia, Myeloid, Acute - therapy Lymphocyte Activation Male Middle Aged Predictive Value of Tests Prognosis T-Lymphocyte Subsets - immunology T-Lymphocytes - immunology
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