Antiviral efficacy analysis of telbivudine concurrent with the first cycle of chemotherapy in HBsAg-positive lymphoma patients

Highlights • Telbivudine concurrent with initial chemotherapy can reduce HBV reactivation. • Telbivudine concurrent with chemotherapy was still effective when rituximab was used. • Even if baseline HBV viral loads are high, concurrent treatment is also effective.

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Veröffentlicht in:Journal of clinical virology 2014-10, Vol.61 (2), p.199-203
Hauptverfasser: Li, Wenyu, Huang, Ling, Guo, Hanguo, Wei, Xiaojuan, Liang, Zhanli
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container_end_page 203
container_issue 2
container_start_page 199
container_title Journal of clinical virology
container_volume 61
creator Li, Wenyu
Huang, Ling
Guo, Hanguo
Wei, Xiaojuan
Liang, Zhanli
description Highlights • Telbivudine concurrent with initial chemotherapy can reduce HBV reactivation. • Telbivudine concurrent with chemotherapy was still effective when rituximab was used. • Even if baseline HBV viral loads are high, concurrent treatment is also effective.
doi_str_mv 10.1016/j.jcv.2014.07.005
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subjects Adolescent
Adult
Aged
Allergy and Immunology
Antineoplastic Agents - adverse effects
Antineoplastic Agents - therapeutic use
Antiviral Agents - therapeutic use
Antiviral therapy
Female
HBsAg-positive lymphoma
HBV reactivation
Hepatitis B Surface Antigens - blood
Hepatitis B virus
Hepatitis B, Chronic - complications
Hepatitis B, Chronic - drug therapy
Humans
Immunocompromised Host
Infectious Disease
Lymphoma - complications
Lymphoma - drug therapy
Male
Middle Aged
Retrospective Studies
Telbivudine
Telbivudine concurrent with chemotherapy
Thymidine - analogs & derivatives
Thymidine - therapeutic use
Treatment Outcome
Virus Activation - drug effects
Young Adult
title Antiviral efficacy analysis of telbivudine concurrent with the first cycle of chemotherapy in HBsAg-positive lymphoma patients
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