Histologic Evaluation of Human Benign Prostatic Hyperplasia Treated by Dutasteride: A Study by Xenograft Model With Improved Severe Combined Immunodeficient Mice

Objective To evaluate histologic change in human prostate samples treated with dutasteride and to elucidate direct effects of dutasteride on human prostate tissue, the present study was conducted by using a xenograft model with improved severe combined immunodeficient (super-SCID) mice, although it...

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Veröffentlicht in:	Urology (Ridgewood, N.J.) N.J.), 2015, Vol.85 (1), p.274.e1-274.e8
Hauptverfasser:	Tsujimura, Akira, Fukuhara, Shinichiro, Soda, Tetsuji, Takezawa, Kentaro, Kiuchi, Hiroshi, Takao, Tetsuya, Miyagawa, Yasushi, Nonomura, Norio, Adachi, Shigeki, Tokita, Yoriko, Nomura, Taisei
Format:	Artikel
Sprache:	eng
Schlagworte:	5-alpha Reductase Inhibitors - therapeutic use Animals Azasteroids - therapeutic use Disease Models, Animal Dutasteride Heterografts Humans Male Mice Mice, SCID Prostatic Hyperplasia - drug therapy Prostatic Hyperplasia - pathology Urology
Online-Zugang:	Volltext
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