Buffy coat volume reduction for optimization of leucapheresis harvests produced by the autoMNC program

Background and Objectives Buffy coat (BC) volume reduction was evaluated in leucapheresis (LA) harvests due to the target monocyte yield and the red blood cell (RBC) content. A packed erythrocyte volume (PEV) of 7·5 ml should not be exceeded to avoid RBC debulking with loss of leucocytes (WBCs) and...

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Veröffentlicht in:	Vox sanguinis 2015-01, Vol.108 (1), p.89-95
Hauptverfasser:	Burk, S., Erdmann, M., Weiss, D., Eckstein, R., Strasser, E. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	apheresis Blood Buffy Coat - cytology Blood Buffy Coat - immunology Blood diseases cellular therapy component production Erythrocytes Female Hematocrit Hematology Humans Leukapheresis - methods Leukapheresis - standards Leukocytes Male
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