Phencyclidine-induced desensitization of striatal dopamine release

Increased release of dopamine (DA) and dihydroxyphenylacetic acid (DOPAC) from slices of striatum of DBA/2J mouse in response to administration of phencyclidine (PCP) in vitro has been observed to be transient, despite continued exposure to PCP. To determinewhether this transient response was a resu...

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Veröffentlicht in:	Neuropharmacology 1992-10, Vol.31 (10), p.1033-1039
Hauptverfasser:	Dwoskin, L.P., Jewell, A.L., Buxton, S.T., Carney, J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dihydroxyphenylacetic Acid - metabolism Animals Biological and medical sciences Cell Survival - drug effects Chromatography, High Pressure Liquid Corpus Striatum - drug effects Corpus Striatum - metabolism desensitization dihydroxyphenylacetic acid dopamine Dopamine - metabolism dopamine release Drug addictions Male Medical sciences Mice Mice, Inbred DBA Neurons - drug effects phencyclidine Phencyclidine - pharmacology striatum Toxicology
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