A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 1993-01, Vol.37 (1), p.19-25
Hauptverfasser:	SULLIVAN, V, BIRON, K. K, TALARICO, C, STANAT, S. C, DAVIS, M, POZZI, L. M, COEN, D. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Action of physical and chemical agents Amino Acid Sequence Base Sequence Biological and medical sciences Cytomegalovirus Cytomegalovirus - drug effects Cytomegalovirus - enzymology Cytomegalovirus - genetics DNA-Directed DNA Polymerase DNA-Directed DNA Polymerase - biosynthesis DNA-Directed DNA Polymerase - genetics Drug Resistance, Microbial Drug Resistance, Microbial - genetics Fundamental and applied biological sciences. Psychology Ganciclovir Ganciclovir - analogs & derivatives Ganciclovir - pharmacology Genes, Viral Genetic Markers Humans Microbiology Molecular Sequence Data Organophosphorus Compounds Organophosphorus Compounds - pharmacology Plasmids Point Mutation Recombination, Genetic Research Article Viral Plaque Assay Virology
Online-Zugang:	Volltext
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