Samter's triad with aural involvement: a novel approach to management
Samter's triad is a well described condition manifesting as chronic rhinosinusitis with nasal polyposis, asthma and aspirin intolerance in a non-atopic individual. The underlying mechanism is still to be fully elucidated. However, aural disease has not been widely reported in these patients. In...
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Veröffentlicht in: | Journal of laryngology and otology 2014-12, Vol.128 (12), p.1114-1116 |
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creator | Sethukumar, P Heywood, R Narula, A |
description | Samter's triad is a well described condition manifesting as chronic rhinosinusitis with nasal polyposis, asthma and aspirin intolerance in a non-atopic individual. The underlying mechanism is still to be fully elucidated. However, aural disease has not been widely reported in these patients. In the few reported cases, most patients underwent major surgery with varying degrees of success.
We report two Samter's triad patients with aural involvement. Both were successfully managed by conservative treatment, thus avoiding the need for major surgery. It appears that more Samter's triad patients may have aural disease than previously thought.
We report good outcomes with conservative treatment, which is relevant because aural disease tends to reoccur in these patients. |
doi_str_mv | 10.1017/S0022215114002722 |
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We report two Samter's triad patients with aural involvement. Both were successfully managed by conservative treatment, thus avoiding the need for major surgery. It appears that more Samter's triad patients may have aural disease than previously thought.
We report good outcomes with conservative treatment, which is relevant because aural disease tends to reoccur in these patients.</description><identifier>ISSN: 0022-2151</identifier><identifier>EISSN: 1748-5460</identifier><identifier>DOI: 10.1017/S0022215114002722</identifier><identifier>PMID: 25418960</identifier><identifier>CODEN: JLOTAX</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adult ; Anti-Inflammatory Agents, Non-Steroidal - adverse effects ; Antibiotics ; Aspirin ; Aspirin - adverse effects ; Asthma ; Asthma - physiopathology ; Asthma - therapy ; Audiometry ; Chronic Disease ; Clinical Records ; Drug Hypersensitivity - etiology ; Ear diseases ; Eardrum ; Endoscopy ; Female ; Hearing loss ; Humans ; Inflammation ; Middle Aged ; Nasal Polyps - physiopathology ; Nasal Polyps - therapy ; Otolaryngology ; Patients ; Polyps ; Sinuses ; Sinusitis - physiopathology ; Sinusitis - therapy ; Steroids ; Surgery ; Treatment Outcome</subject><ispartof>Journal of laryngology and otology, 2014-12, Vol.128 (12), p.1114-1116</ispartof><rights>Copyright © JLO (1984) Limited 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-cc04f09dda10945ec89c84e1036a7d522869c667229a8201b7f51b8b50c5e7f53</citedby><cites>FETCH-LOGICAL-c443t-cc04f09dda10945ec89c84e1036a7d522869c667229a8201b7f51b8b50c5e7f53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0022215114002722/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,777,781,27905,27906,55609</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25418960$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sethukumar, P</creatorcontrib><creatorcontrib>Heywood, R</creatorcontrib><creatorcontrib>Narula, A</creatorcontrib><title>Samter's triad with aural involvement: a novel approach to management</title><title>Journal of laryngology and otology</title><addtitle>J. Laryngol. Otol</addtitle><description>Samter's triad is a well described condition manifesting as chronic rhinosinusitis with nasal polyposis, asthma and aspirin intolerance in a non-atopic individual. The underlying mechanism is still to be fully elucidated. However, aural disease has not been widely reported in these patients. In the few reported cases, most patients underwent major surgery with varying degrees of success.
We report two Samter's triad patients with aural involvement. Both were successfully managed by conservative treatment, thus avoiding the need for major surgery. It appears that more Samter's triad patients may have aural disease than previously thought.
We report good outcomes with conservative treatment, which is relevant because aural disease tends to reoccur in these patients.</description><subject>Adult</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - adverse effects</subject><subject>Antibiotics</subject><subject>Aspirin</subject><subject>Aspirin - adverse effects</subject><subject>Asthma</subject><subject>Asthma - physiopathology</subject><subject>Asthma - therapy</subject><subject>Audiometry</subject><subject>Chronic Disease</subject><subject>Clinical Records</subject><subject>Drug Hypersensitivity - etiology</subject><subject>Ear diseases</subject><subject>Eardrum</subject><subject>Endoscopy</subject><subject>Female</subject><subject>Hearing loss</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Middle Aged</subject><subject>Nasal Polyps - physiopathology</subject><subject>Nasal Polyps - therapy</subject><subject>Otolaryngology</subject><subject>Patients</subject><subject>Polyps</subject><subject>Sinuses</subject><subject>Sinusitis - physiopathology</subject><subject>Sinusitis - therapy</subject><subject>Steroids</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><issn>0022-2151</issn><issn>1748-5460</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kEtPwzAQhC0EoqXwA7ggSxzgElg7tpNwQ1V5SJU4FM7RxnHbVHkUOyni3-PQghCIk1eab8a7Q8gpgysGLLqeAXDOmWRM-CnifI8MWSTiQAoF-2TYy0GvD8iRcysAbwJ-SAZcChYnCoZkMsOqNfbC0dYWmNO3ol1S7CyWtKg3TbkxlanbG4q0bjampLhe2wb1krYNrbDGxad-TA7mWDpzsntH5OVu8jx-CKZP94_j22mghQjbQGsQc0jyHBkkQhodJzoWhkGoMMol57FKtFL-kARjDiyL5pJlcSZBS-PncEQut7l-idfOuDatCqdNWWJtms6lTIWRVKEME4-e_0JXTWdrv11PKc5FAj3FtpS2jXPWzNO1LSq07ymDtO84_dOx95ztkrusMvm346tUD4S7UKwyW-QL8-Pvf2M_AME3g2M</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Sethukumar, P</creator><creator>Heywood, R</creator><creator>Narula, A</creator><general>Cambridge University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>20141201</creationdate><title>Samter's triad with aural involvement: a novel approach to management</title><author>Sethukumar, P ; Heywood, R ; Narula, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443t-cc04f09dda10945ec89c84e1036a7d522869c667229a8201b7f51b8b50c5e7f53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - adverse effects</topic><topic>Antibiotics</topic><topic>Aspirin</topic><topic>Aspirin - adverse effects</topic><topic>Asthma</topic><topic>Asthma - physiopathology</topic><topic>Asthma - therapy</topic><topic>Audiometry</topic><topic>Chronic Disease</topic><topic>Clinical Records</topic><topic>Drug Hypersensitivity - etiology</topic><topic>Ear diseases</topic><topic>Eardrum</topic><topic>Endoscopy</topic><topic>Female</topic><topic>Hearing loss</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Middle Aged</topic><topic>Nasal Polyps - physiopathology</topic><topic>Nasal Polyps - therapy</topic><topic>Otolaryngology</topic><topic>Patients</topic><topic>Polyps</topic><topic>Sinuses</topic><topic>Sinusitis - physiopathology</topic><topic>Sinusitis - therapy</topic><topic>Steroids</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sethukumar, P</creatorcontrib><creatorcontrib>Heywood, R</creatorcontrib><creatorcontrib>Narula, A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of laryngology and otology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sethukumar, P</au><au>Heywood, R</au><au>Narula, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Samter's triad with aural involvement: a novel approach to management</atitle><jtitle>Journal of laryngology and otology</jtitle><addtitle>J. Laryngol. Otol</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>128</volume><issue>12</issue><spage>1114</spage><epage>1116</epage><pages>1114-1116</pages><issn>0022-2151</issn><eissn>1748-5460</eissn><coden>JLOTAX</coden><abstract>Samter's triad is a well described condition manifesting as chronic rhinosinusitis with nasal polyposis, asthma and aspirin intolerance in a non-atopic individual. The underlying mechanism is still to be fully elucidated. However, aural disease has not been widely reported in these patients. In the few reported cases, most patients underwent major surgery with varying degrees of success.
We report two Samter's triad patients with aural involvement. Both were successfully managed by conservative treatment, thus avoiding the need for major surgery. It appears that more Samter's triad patients may have aural disease than previously thought.
We report good outcomes with conservative treatment, which is relevant because aural disease tends to reoccur in these patients.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>25418960</pmid><doi>10.1017/S0022215114002722</doi><tpages>3</tpages></addata></record> |
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subjects | Adult Anti-Inflammatory Agents, Non-Steroidal - adverse effects Antibiotics Aspirin Aspirin - adverse effects Asthma Asthma - physiopathology Asthma - therapy Audiometry Chronic Disease Clinical Records Drug Hypersensitivity - etiology Ear diseases Eardrum Endoscopy Female Hearing loss Humans Inflammation Middle Aged Nasal Polyps - physiopathology Nasal Polyps - therapy Otolaryngology Patients Polyps Sinuses Sinusitis - physiopathology Sinusitis - therapy Steroids Surgery Treatment Outcome |
title | Samter's triad with aural involvement: a novel approach to management |
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