Effects of MK 801 on morphine physical dependence: Attenuation and intensification

It has previously been reported that the noncompetitive NMDA receptor antagonists ketamine and dextromethorphan suppressed the naloxone-induced morphine abstinence syndrome. In addition, the previous blockade by ketamine and dextromethorphan of NMDA receptors has been shown to intensify the naloxone...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1992-10, Vol.43 (2), p.487-490
Hauptverfasser:	Koyuncuoǧlu, H., Dizdar, Y., Aricioǧlu, F., Sayin, Ü.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Attenuation of precipitated abstinence syndrome Biological and medical sciences Dextromethorphan - pharmacology Dizocilpine Maleate - pharmacology Drug addictions Intensification of morphine dependence Ketamine - pharmacology Male Medical sciences MK 801 Morphine - pharmacology Morphine Dependence - psychology Rats Rats, Wistar Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors Substance Withdrawal Syndrome - physiopathology Toxicology
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