Nuclear matrix attachment regions and plant gene expression
Higher-order chromatin organization is presumed to be mediated in part by DNA sequences that bind to the insoluble nuclear matrix. The function of these ‘matrix attachment regions’ (MARs) has been investigated in transgenic plants. The studies indicated that MARs can reduce variation in, and increas...
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| Veröffentlicht in: | Trends in plant science 1998-03, Vol.3 (3), p.91-97 |
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| container_title | Trends in plant science |
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| creator | Holmes-Davis, Rachel Comai, Luca |
| description | Higher-order chromatin organization is presumed to be mediated in part by DNA sequences that bind to the insoluble nuclear matrix. The function of these ‘matrix attachment regions’ (MARs) has been investigated in transgenic plants. The studies indicated that MARs can reduce variation in, and increase, transgene expression levels. However, the hypothesis that MARs fix chromatin loops to the nuclear matrix and insulate regulatory domains presently lacks firm confirmatory evidence, and alternative models and experimental approaches need to be considered. |
| doi_str_mv | 10.1016/S1360-1385(98)01198-4 |
| format | Article |
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| ispartof | Trends in plant science, 1998-03, Vol.3 (3), p.91-97 |
| issn | 1360-1385 1878-4372 |
| language | eng |
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| source | Elsevier ScienceDirect Journals |
| subjects | Biological and medical sciences Cell biochemistry Cell physiology Fundamental and applied biological sciences. Psychology Gene expression Molecular and cellular biology Molecular genetics Plant physiology and development |
| title | Nuclear matrix attachment regions and plant gene expression |
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