Binding of Bacterial Peptidoglycan to CD14

The hypothesis that soluble peptidoglycan (sPGN, a macrophage-activator from Gram-positive bacteria) binds to CD14 (a lipopolysaccharide (LPS) receptor) was tested. sPGN specifically bound to CD14 in the following three assays: binding of soluble32P-CD14 (sCD14) to agarose-immobilized sPGN, enzyme-l...

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Veröffentlicht in:	The Journal of biological chemistry 1998-04, Vol.273 (15), p.8680-8690
Hauptverfasser:	Dziarski, Roman, Tapping, Richard I., Tobias, Peter S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding, Competitive Cell Line Escherichia coli - metabolism Gram-Positive Bacteria - metabolism Humans Insecta Kinetics Lipopolysaccharide Receptors - metabolism Lipopolysaccharides - metabolism Peptidoglycan - metabolism Recombinant Proteins - metabolism Salmonella - metabolism Sepharose Staphylococcus aureus - metabolism Streptococcus - metabolism Teichoic Acids - metabolism Transfection
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