Substrate topography determines the fate of chondrogenesis from human mesenchymal stem cells resulting in specific cartilage phenotype formation

Abstract To reproduce a complex and functional tissue, it is crucial to provide a biomimetic cellular microenvironment that not only incorporates biochemical cues, but also physical features including the nano-topographical patterning, for cell/matrix interaction. We developed spatially-controlled n...

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Veröffentlicht in:	Nanomedicine 2014-10, Vol.10 (7), p.1507-1516
Hauptverfasser:	Wu, Ying-Nan, MSc, Law, Jaslyn Bee Khuan, PhD, He, Ai Yu, BSc, Low, Hong Yee, PhD, Hui, James H.P., MD, Lim, Chwee Teck, PhD, Yang, Zheng, PhD, Lee, Eng Hin, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Cartilage - cytology Cell Lineage Cell Proliferation Chondrogenesis Humans Internal Medicine Mesenchymal stem cell Mesenchymal Stromal Cells - cytology Microscopy, Atomic Force Microscopy, Electron, Scanning Nanotopography Tissue Scaffolds Zonal cartilage
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