Resveratrol prevents social deficits in animal model of autism induced by valproic acid

•We performed a prenatal treatment with resveratrol in a rodent model of autism.•Resveratrol prevented autistic-like social behaviors.•Bioinformatics analysis suggests weak and unstable interactions between RSV and VPA.•These results suggest cellular effects instead of a single chemical process.•Inv...

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Veröffentlicht in:	Neuroscience letters 2014-11, Vol.583, p.176-181
Hauptverfasser:	Bambini-Junior, Victorio, Zanatta, Geancarlo, Della Flora Nunes, Gustavo, Mueller de Melo, Gabriela, Michels, Marcus, Fontes-Dutra, Mellanie, Nogueira Freire, Valder, Riesgo, Rudimar, Gottfried, Carmem
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal model Animals Anti-Inflammatory Agents - therapeutic use Autism spectrum disorder Autistic Disorder - drug therapy Autistic Disorder - psychology Behavior Female Male Maternal Exposure Molecular Dynamics Simulation Pregnancy Prenatal Exposure Delayed Effects - drug therapy Prenatal Exposure Delayed Effects - psychology Rats, Wistar Resveratrol Social Skills Stilbenes - therapeutic use Valproate Valproic Acid - adverse effects
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