The Dual RAF/MEK Inhibitor CH5126766/RO5126766 May Be a Potential Therapy for RAS-Mutated Tumor Cells: e113217

Although melanoma is the most aggressive skin cancer, recent advances in BRAF and/or MEK inhibitors against BRAF-mutated melanoma have improved survival rates. Despite these advances, a treatment strategy targeting NRAS-mutated melanoma has not yet been elucidated. We discovered CH5126766/RO5126766...

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Veröffentlicht in:PloS one 2014-11, Vol.9 (11)
Hauptverfasser: Wada, Makoto, Horinaka, Mano, Yamazaki, Toshikazu, Katoh, Norito, Sakai, Toshiyuki
Format: Artikel
Sprache:eng
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