A preliminary investigation of computed tomographic angiography in the assessment of coronary artery distensibility
To test 2 hypotheses: first, that coronary distensibility can be measured noninvasively using 64-slice computed tomographic angiography (CTA); and second, that the extent of coronary artery disease (CAD) in any individual patient is related to the degree of distensibility detected by CTA. Computed t...
Gespeichert in:
| Veröffentlicht in: | Journal of computer assisted tomography 2014-05, Vol.38 (3), p.439-443 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 443 |
|---|---|
| container_issue | 3 |
| container_start_page | 439 |
| container_title | Journal of computer assisted tomography |
| container_volume | 38 |
| creator | Zhang, Jia-Yin Li, Yue-Hua Li, Ming-Hua Pan, Jing-Wei |
| description | To test 2 hypotheses: first, that coronary distensibility can be measured noninvasively using 64-slice computed tomographic angiography (CTA); and second, that the extent of coronary artery disease (CAD) in any individual patient is related to the degree of distensibility detected by CTA.
Computed tomographic angiography was performed in 30 healthy adults and in 30 patients. All subjects were younger than 55 years. The main lesion located in the left anterior descending branch in patients with CAD. The cross-sectional coronary area of the left main and the left anterior descending arteries were measured in each phase (5%-95%, 10% each), and any change in the ratio was quantified. A distensibility value (D value) was determined for each artery.
Compared with healthy subjects, the coronary area of the patients with CAD was significantly decreased in 65% to 85% (P < 0.05). There was a significant difference in the D value between healthy subjects and patients with both single-vessel and 2-vessel disease (P < 0.05).
Coronary artery distensibility can be measured noninvasively using data obtained from CTA. The distensibility of the coronary artery decreased with the increasing number of involved pathological coronary vessels. The distensibility of the coronary artery correlated with the extent of CAD. |
| doi_str_mv | 10.1097/RCT.0000000000000068 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1635036690</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1635036690</sourcerecordid><originalsourceid>FETCH-LOGICAL-c289t-512576237c625538d69a943e54554514c597c18f076ae845daa8615e2dc3f7c43</originalsourceid><addsrcrecordid>eNqFUV1LwzAUDaK4Of0HInn0pTNpPvs4hl8wEGQ-lyxNt0jb1CQV_Pdmdgr64uXC5cI593LOAeASozlGhbh5Xq7n6FdxeQSmmJE8I5iyYzBFhJNMCswm4CyEV4SwIISegklOucSSoykIC9h709jWdsp_QNu9mxDtVkXrOuhqqF3bD9FUMLrWbb3qd1ZD1W3tuOwZMO4MVCGYEFrTxZHl3dc95aNJo7Ihmi7YjW1s_DgHJ7Vqgrk4zBl4ubtdLx-y1dP943KxynQui5gxnDPBcyI0zxkjsuKFKigxjLLUmGpWCI1ljQRXRlJWKSU5ZiavNKmFpmQGrse7vXdvQ9JVtjZo0zSqM24IJeaEJYt4gf6HMiKwRCIZOgN0hGrvQvCmLntv2yS2xKjcJ1OmZMq_ySTa1eHDsGlN9UP6joJ8AuoWilI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1537180736</pqid></control><display><type>article</type><title>A preliminary investigation of computed tomographic angiography in the assessment of coronary artery distensibility</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Zhang, Jia-Yin ; Li, Yue-Hua ; Li, Ming-Hua ; Pan, Jing-Wei</creator><creatorcontrib>Zhang, Jia-Yin ; Li, Yue-Hua ; Li, Ming-Hua ; Pan, Jing-Wei</creatorcontrib><description>To test 2 hypotheses: first, that coronary distensibility can be measured noninvasively using 64-slice computed tomographic angiography (CTA); and second, that the extent of coronary artery disease (CAD) in any individual patient is related to the degree of distensibility detected by CTA.
Computed tomographic angiography was performed in 30 healthy adults and in 30 patients. All subjects were younger than 55 years. The main lesion located in the left anterior descending branch in patients with CAD. The cross-sectional coronary area of the left main and the left anterior descending arteries were measured in each phase (5%-95%, 10% each), and any change in the ratio was quantified. A distensibility value (D value) was determined for each artery.
Compared with healthy subjects, the coronary area of the patients with CAD was significantly decreased in 65% to 85% (P < 0.05). There was a significant difference in the D value between healthy subjects and patients with both single-vessel and 2-vessel disease (P < 0.05).
Coronary artery distensibility can be measured noninvasively using data obtained from CTA. The distensibility of the coronary artery decreased with the increasing number of involved pathological coronary vessels. The distensibility of the coronary artery correlated with the extent of CAD.</description><identifier>ISSN: 0363-8715</identifier><identifier>EISSN: 1532-3145</identifier><identifier>DOI: 10.1097/RCT.0000000000000068</identifier><identifier>PMID: 24681860</identifier><language>eng</language><publisher>United States</publisher><subject>Algorithms ; Coronary Angiography - methods ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - physiopathology ; Coronary Vessels - physiopathology ; Female ; Humans ; Male ; Middle Aged ; Pilot Projects ; Radiographic Image Interpretation, Computer-Assisted - methods ; Reproducibility of Results ; Sensitivity and Specificity ; Tomography, X-Ray Computed - methods ; Vascular Resistance ; Vascular Stiffness</subject><ispartof>Journal of computer assisted tomography, 2014-05, Vol.38 (3), p.439-443</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c289t-512576237c625538d69a943e54554514c597c18f076ae845daa8615e2dc3f7c43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24681860$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Jia-Yin</creatorcontrib><creatorcontrib>Li, Yue-Hua</creatorcontrib><creatorcontrib>Li, Ming-Hua</creatorcontrib><creatorcontrib>Pan, Jing-Wei</creatorcontrib><title>A preliminary investigation of computed tomographic angiography in the assessment of coronary artery distensibility</title><title>Journal of computer assisted tomography</title><addtitle>J Comput Assist Tomogr</addtitle><description>To test 2 hypotheses: first, that coronary distensibility can be measured noninvasively using 64-slice computed tomographic angiography (CTA); and second, that the extent of coronary artery disease (CAD) in any individual patient is related to the degree of distensibility detected by CTA.
Computed tomographic angiography was performed in 30 healthy adults and in 30 patients. All subjects were younger than 55 years. The main lesion located in the left anterior descending branch in patients with CAD. The cross-sectional coronary area of the left main and the left anterior descending arteries were measured in each phase (5%-95%, 10% each), and any change in the ratio was quantified. A distensibility value (D value) was determined for each artery.
Compared with healthy subjects, the coronary area of the patients with CAD was significantly decreased in 65% to 85% (P < 0.05). There was a significant difference in the D value between healthy subjects and patients with both single-vessel and 2-vessel disease (P < 0.05).
Coronary artery distensibility can be measured noninvasively using data obtained from CTA. The distensibility of the coronary artery decreased with the increasing number of involved pathological coronary vessels. The distensibility of the coronary artery correlated with the extent of CAD.</description><subject>Algorithms</subject><subject>Coronary Angiography - methods</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary Artery Disease - physiopathology</subject><subject>Coronary Vessels - physiopathology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pilot Projects</subject><subject>Radiographic Image Interpretation, Computer-Assisted - methods</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Vascular Resistance</subject><subject>Vascular Stiffness</subject><issn>0363-8715</issn><issn>1532-3145</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUV1LwzAUDaK4Of0HInn0pTNpPvs4hl8wEGQ-lyxNt0jb1CQV_Pdmdgr64uXC5cI593LOAeASozlGhbh5Xq7n6FdxeQSmmJE8I5iyYzBFhJNMCswm4CyEV4SwIISegklOucSSoykIC9h709jWdsp_QNu9mxDtVkXrOuhqqF3bD9FUMLrWbb3qd1ZD1W3tuOwZMO4MVCGYEFrTxZHl3dc95aNJo7Ihmi7YjW1s_DgHJ7Vqgrk4zBl4ubtdLx-y1dP943KxynQui5gxnDPBcyI0zxkjsuKFKigxjLLUmGpWCI1ljQRXRlJWKSU5ZiavNKmFpmQGrse7vXdvQ9JVtjZo0zSqM24IJeaEJYt4gf6HMiKwRCIZOgN0hGrvQvCmLntv2yS2xKjcJ1OmZMq_ySTa1eHDsGlN9UP6joJ8AuoWilI</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>Zhang, Jia-Yin</creator><creator>Li, Yue-Hua</creator><creator>Li, Ming-Hua</creator><creator>Pan, Jing-Wei</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20140501</creationdate><title>A preliminary investigation of computed tomographic angiography in the assessment of coronary artery distensibility</title><author>Zhang, Jia-Yin ; Li, Yue-Hua ; Li, Ming-Hua ; Pan, Jing-Wei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c289t-512576237c625538d69a943e54554514c597c18f076ae845daa8615e2dc3f7c43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Algorithms</topic><topic>Coronary Angiography - methods</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Coronary Artery Disease - physiopathology</topic><topic>Coronary Vessels - physiopathology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pilot Projects</topic><topic>Radiographic Image Interpretation, Computer-Assisted - methods</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Vascular Resistance</topic><topic>Vascular Stiffness</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Jia-Yin</creatorcontrib><creatorcontrib>Li, Yue-Hua</creatorcontrib><creatorcontrib>Li, Ming-Hua</creatorcontrib><creatorcontrib>Pan, Jing-Wei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of computer assisted tomography</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Jia-Yin</au><au>Li, Yue-Hua</au><au>Li, Ming-Hua</au><au>Pan, Jing-Wei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A preliminary investigation of computed tomographic angiography in the assessment of coronary artery distensibility</atitle><jtitle>Journal of computer assisted tomography</jtitle><addtitle>J Comput Assist Tomogr</addtitle><date>2014-05-01</date><risdate>2014</risdate><volume>38</volume><issue>3</issue><spage>439</spage><epage>443</epage><pages>439-443</pages><issn>0363-8715</issn><eissn>1532-3145</eissn><abstract>To test 2 hypotheses: first, that coronary distensibility can be measured noninvasively using 64-slice computed tomographic angiography (CTA); and second, that the extent of coronary artery disease (CAD) in any individual patient is related to the degree of distensibility detected by CTA.
Computed tomographic angiography was performed in 30 healthy adults and in 30 patients. All subjects were younger than 55 years. The main lesion located in the left anterior descending branch in patients with CAD. The cross-sectional coronary area of the left main and the left anterior descending arteries were measured in each phase (5%-95%, 10% each), and any change in the ratio was quantified. A distensibility value (D value) was determined for each artery.
Compared with healthy subjects, the coronary area of the patients with CAD was significantly decreased in 65% to 85% (P < 0.05). There was a significant difference in the D value between healthy subjects and patients with both single-vessel and 2-vessel disease (P < 0.05).
Coronary artery distensibility can be measured noninvasively using data obtained from CTA. The distensibility of the coronary artery decreased with the increasing number of involved pathological coronary vessels. The distensibility of the coronary artery correlated with the extent of CAD.</abstract><cop>United States</cop><pmid>24681860</pmid><doi>10.1097/RCT.0000000000000068</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0363-8715 |
| ispartof | Journal of computer assisted tomography, 2014-05, Vol.38 (3), p.439-443 |
| issn | 0363-8715 1532-3145 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1635036690 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Algorithms Coronary Angiography - methods Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - physiopathology Coronary Vessels - physiopathology Female Humans Male Middle Aged Pilot Projects Radiographic Image Interpretation, Computer-Assisted - methods Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed - methods Vascular Resistance Vascular Stiffness |
| title | A preliminary investigation of computed tomographic angiography in the assessment of coronary artery distensibility |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T00%3A25%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20preliminary%20investigation%20of%20computed%20tomographic%20angiography%20in%20the%20assessment%20of%20coronary%20artery%20distensibility&rft.jtitle=Journal%20of%20computer%20assisted%20tomography&rft.au=Zhang,%20Jia-Yin&rft.date=2014-05-01&rft.volume=38&rft.issue=3&rft.spage=439&rft.epage=443&rft.pages=439-443&rft.issn=0363-8715&rft.eissn=1532-3145&rft_id=info:doi/10.1097/RCT.0000000000000068&rft_dat=%3Cproquest_cross%3E1635036690%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1537180736&rft_id=info:pmid/24681860&rfr_iscdi=true |