Architecture of the Saccharomyces cerevisiae RNA polymerase I Core Factor complex

Chemical cross-linking MS and supporting biochemical and genetic analyses reveal the architecture of the yeast Core Factor complex and suggest how it directs transcription of RNA Pol I at rDNA promoters. Core Factor (CF) is a conserved RNA polymerase (Pol) I general transcription factor comprising R...

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Veröffentlicht in:	Nature structural & molecular biology 2014-09, Vol.21 (9), p.810-816
Hauptverfasser:	Knutson, Bruce A, Luo, Jie, Ranish, Jeffrey, Hahn, Steven
Format:	Artikel
Sprache:	eng
Schlagworte:	101/58 631/45/612/822 Analysis Biochemistry Biological Microscopy Eukaryotes Genetic aspects Genetic research Genetics Life Sciences Membrane Biology Models, Molecular Molecular biology Molecular structure Pol1 Transcription Initiation Complex Proteins - chemistry Pol1 Transcription Initiation Complex Proteins - metabolism Protein binding Protein research Protein Structure Protein Structure, Tertiary Protein Subunits - chemistry Protein Subunits - metabolism RNA polymerase RNA Polymerase I - chemistry RNA Polymerase I - metabolism RNA polymerases Saccharomyces Saccharomyces cerevisiae Saccharomyces cerevisiae - chemistry Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - metabolism Structure Yeast
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